N-[2-[4-(2-甲氧基苯基)-1-哌嗪基]乙基]-N-2-吡啶基-环己烷羧胺合成路线 (共 6 条)
反应条件
triethylamine in acetonitrile
参考文献
O'Connor, Naphtali A.; Paisner, David A.; Huryn, Donna; Shea, Kenneth J.
Journal of the American Chemical Society, 2007 , vol. 129, # 6 p. 1680 - 1689
反应条件
1: 90 percent / LiAlH4 / tetrahydrofuran 2: 86 percent / Et3N / acetonitrile View Scheme
参考文献
Journal of the American Chemical Society, , vol. 129, # 6 p. 1680 - 1689
反应条件
1: 56 percent / acetonitrile 2: 83 percent / K2CO3 / dimethylformamide 3: 90 percent / LiAlH4 / tetrahydrofuran 4: 86 percent / Et3N / acetonitrile View Scheme
参考文献
Journal of the American Chemical Society, , vol. 129, # 6 p. 1680 - 1689
反应条件
1: 91 percent / potassium carbonate, / dimethylformamide / 18 h 2: 89 percent / BH3-Me2S / tetrahydrofuran / 2.5 h / Heating 3: 60 percent / triethylamine / CH2Cl2 / 20 °C View Scheme
参考文献
Medicinal Chemistry Research, , vol. 5, # 2/3 p. 208 - 227
反应条件
N-cyclohexylcarbodiimide-N'-propyloxymethyl polystyrene in tetrahydrofuran T=100°C; 0.166667 h; microwave irradiation;
参考文献
Journal of Labelled Compounds and Radiopharmaceuticals, , vol. 46, p. S229 - S229
反应条件
1: 91 percent / potassium carbonate, / dimethylformamide / 18 h 2: 89 percent / BH3-Me2S / tetrahydrofuran / 2.5 h / Heating 3: 60 percent / triethylamine / CH2Cl2 / 20 °C View Scheme
参考文献
Medicinal Chemistry Research, , vol. 5, # 2/3 p. 208 - 227