反应条件
1: 95 percent / phosphorus pentoxide / CH2Cl2 / Ambient temperature 2: 1) CH3Li*LiBr / 1) THF, RT, 3.5 h, 2) THF, HMPA, RT, 30 min 3: KF*2H2O / dimethylformamide / 0.5 h / Ambient temperature 4: 1) n-butyllithium / 1) THF, -23 deg C, 1 h, 2) THF, HMPA, 2.1) -23 deg C, 30 min., 2.2) RT, 1.5 h 5: 91 percent / 37percent HCl / methanol / Ambient temperature 6: 86 percent / pyridinium dichromate / dimethylformamide / Ambient temperature View Scheme
参考文献
Xu, Zhenchun; Byun, Hoe-Sup; Bittman, Robert
Journal of Organic Chemistry, 1991 , vol. 56, # 25 p. 7183 - 7186
