2,6-二氯异烟酸乙酯合成路线

参考文献

Kumar, Rohan J.; Karlsson, Susanne; Streich, Daniel; Jensen, Alice Rolandini; Jaeger, Michael; Becker, Hans-Christian; Bergquist, Jonas; Johansson, Olof; Hammarstroem, Leif
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75308-46-22,6-二氯吡啶-4-甲酸叔丁酯+

64-17-5乙醇

1604-14-42,6-二氯异烟酸乙酯

参考文献

ACTELION PHARMACEUTICALS LTD
Patent: WO2009/24905 A1, 2009 ;
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WO 2009/024905 A1

64-17-5乙醇+

42521-08-42,6-二氯吡啶-4-羰酰氯

1604-14-42,6-二氯异烟酸乙酯

参考文献

Phillips, Gary; Guilford, William J.; Buckman, Brad O.; Davey, David D.; Eagen, Keith A.; Koovakkat, Sunil; Liang, Amy; McCarrick, Meg; Mohan, Raju; Ng, Howard P.; Pinkerton, Michael; Subramanyam, Babu; Ho, Elena; Trinh, Lan; Whitlow, Marc; Wu, Shung; Xu, Wei; Morrissey, Michael M.
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101990-72-12,6-二氯-4-氯甲基吡啶

1604-14-42,6-二氯异烟酸乙酯

参考文献

Ciba-Geigy Corporation
Patent: US4968344 A1, 1990 ;

7664-93-9硫酸+

5398-44-72,6-二氯异烟酸

1604-14-42,6-二氯异烟酸乙酯

参考文献

The Wellcome Foundation Limited
Patent: US5202356 A1, 1993 ;

125850-02-43,5-二氯-2H-1,4-恶嗪-2-酮+

623-47-2丙炔酸乙酯

1604-14-42,6-二氯异烟酸乙酯+

58584-86-42,6-二氯烟酸乙酯

参考文献

Meerpoel; Deroover; Van Aken; Lux; Hoornaert
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99-11-6柠嗪酸

1604-14-42,6-二氯异烟酸乙酯

参考文献

Abdel Salam, Osama I.; Khalifa, Nagy M.; Said, Said A.; Amr, Abd El-Galil E.
Research on Chemical Intermediates, 2014 , vol. 40, # 3 p. 1147 - 1155

1604-14-42,6-二氯异烟酸乙酯+

58584-86-42,6-二氯烟酸乙酯

参考文献

Tutonda, M.; Vanderzande, D.; Hendrickx, M.; Hoornaert, G.
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1604-14-42,6-二氯异烟酸乙酯

372520-85-96,6''-二(溴甲基)-[2,2':6',2''-三联吡啶]-4'-羧酸乙酯

参考文献

Galaup, Chantal; Couchet, Jean-Marc; Bedel, Sebastien; Tisnes, Pierre; Picard, Claude
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1604-14-42,6-二氯异烟酸乙酯

113293-70-22,6-二氯吡啶-4-甲醛

参考文献

ABBOTT LABORATORIES; ABBOTT LABORATORIES TRADING (SHANGHAI) COMPANY, LTD.; VASUDEVAN, Anil; PENNING, Thomas Dale; CHEN, Huanming; LIANG, Bo; WANG, Shaohui; ZHAO, Zhongqiang; CHAI, Dikun; YANG, Leifu; GAO, Yingxiang
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