5-(4-氯苄亚基)-2,2-二甲基-1,3-二恶烷-4,6-二酮合成路线 （共 13 条）
反应条件
in various solvent(s) T=20°C; Knoevenagel condensation; 2 h;
参考文献
Hu, Yi; Wei, Ping; Huang, He; Le, Zhang-Gao; Chen, Zhen-Chu
Synthetic Communications, 2005 , vol. 35, # 23 p. 2955 - 2960
反应条件
in ethanol 0.333333 h; RefluxGreen chemistry;
参考文献
Kumar, Dhruva; Suresh; Sandhu, Jagir S.
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2013 , vol. 52, # 8 p. 1157 - 1160
反应条件
in N,N-dimethyl-formamide T=80°C; Condensation; Knoevenagel condensation; 1 h;
参考文献
Shi, Daqing; Wang, Yucheng; Lu, Zaisheng; Dai, Guiyuan
Synthetic Communications, 2000 , vol. 30, # 4 p. 713 - 726
反应条件
in acetonitrile T=20°C; Knoevenagel condensation;
参考文献
Wang, Qi-Fang; Hui, Li; Hou, Hong; Yan, Chao-Guo
Journal of Combinatorial Chemistry, 2010 , vol. 12, # 2 p. 260 - 265
反应条件
in acetonitrile T=20°C; Knoevenagel condensation;
参考文献
Wang, Qi-Fang; Hui, Li; Hou, Hong; Yan, Chao-Guo
Journal of Combinatorial Chemistry, 2010 , vol. 12, # 2 p. 260 - 265
反应条件
in acetonitrile T=20°C; Knoevenagel condensation;
参考文献
Wang, Qi-Fang; Hui, Li; Hou, Hong; Yan, Chao-Guo
Journal of Combinatorial Chemistry, 2010 , vol. 12, # 2 p. 260 - 265
反应条件
in acetonitrile T=20°C; Knoevenagel condensation;
参考文献
Wang, Qi-Fang; Hui, Li; Hou, Hong; Yan, Chao-Guo
Journal of Combinatorial Chemistry, 2010 , vol. 12, # 2 p. 260 - 265
参考文献
Fillion, Eric; Dumas, Aaron M.; Hogg, Sylvia A.
Journal of Organic Chemistry, 2006 , vol. 71, # 26 p. 9899 - 9902
反应条件
1: 5-(4-chlorobenzyl)-2,2-dimethyl[1,3]dioxane-4,6-dione With potassium hydride in acetonitrile T=20°C; 0.333333 h; Inert atmosphereGlovebox; 2: 4-acetylamino-2,2,6,6-tetramethylpiperidine-1-oxoammonium in acetonitrile T=24.84°C; Inert atmosphereGlovebox; Thermodynamic data;
参考文献
Cao, Ying; Zhang, Song-Chen; Zhang, Min; Shen, Guang-Bin; Zhu, Xiao-Qing
Journal of Organic Chemistry, 2013 , vol. 78, # 14 p. 7154 - 7168
反应条件
1: With sodium tetrahydroborate; acetic acid in dichloromethane T=20°C; 1 h; Inert atmosphere; 2: With phenyl silane; triethylamine in tetrahydrofuran T=20°C; 2 h; Inert atmosphere;
参考文献
Liu, Kai; Rao, Wei; Parikh, Hardik; Li, Qianbin; Guo, Tai L.; Grant, Steven; Kellogg, Glen E.; Zhang, Shijun
European Journal of Medicinal Chemistry, 2012 , vol. 47, # 1 p. 125 - 137
