sodium in toluene

sodium in toluene

potassium tert-butylate in N,N,N',N',N'',N''-hexamethylphosphoric triamide T=0°C; 2 h;

iodine cloride

potassium fluoride in N,N,N',N',N'',N''-hexamethylphosphoric triamide T=100°C; 96 h;

potassium fluoride in N,N,N',N',N'',N''-hexamethylphosphoric triamide T=80°C; P=38000 Torr;

1: Na / toluene 2: Br2 View Scheme

potassium fluoride in N,N,N',N',N'',N''-hexamethylphosphoric triamide T=80°C; 12 h;

<b>Multi-step reaction with 2 steps<br /> </b>1: 29 percent / tBuLi / tetrahydrofuran; pentane / 1.5 h / -100 - -75 &deg;C<br />2: 3.4 percent / s-BuLi / tetrahydrofuran; cyclohexane / 1.5 h / -100 - -75 &deg;C<br /> <br /> &nbsp;

Stage #1: <a href="#" onclick="return RXDsubstances(event, this, '605632', constants.ctx, '0')">chlorobenzene</a> <b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '3587206', constants.ctx, '0')">sec.-butyllithium</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '102391', constants.ctx, '0')">tetrahydrofuran</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '1900225', constants.ctx, '0')">cyclohexane</a> <br />T=-100&deg;C;&nbsp;2&nbsp;h;&nbsp;<br />Stage #2: <a href="#" onclick="return RXDsubstances(event, this, '1209232', constants.ctx, '0')">chloro-trimethyl-silane</a> &nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '102391', constants.ctx, '0')">tetrahydrofuran</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '1900225', constants.ctx, '0')">cyclohexane</a> <br /> <br /> &nbsp;