(R)-(+)-1-苯基-1-丙醇合成路线 （共 130 条）
反应条件
potassium tert-butylate; hydrogen; [Ru(η4-COD)(η3-methylallyl)2]; (R)-Ph-BINAN-H-Py in isopropyl alcohol T=25°C; P=38000 Torr; 18 h;
参考文献
Journal of the American Chemical Society, , vol. 128, # 27 p. 8716 - 8717
反应条件
P-1-(4',6'-dimethyl-2'-hydroxyphenyl)-2-(N,N-di-n-butylaminomethyl)naphthalene in hexane T=20°C; 16 h;
参考文献
Tetrahedron Asymmetry, , vol. 9, # 4 p. 667 - 679
反应条件
polymer-supported (1R,2S)-ephedrine in toluene T=20°C; Addition; 12 h;
参考文献
Journal of the Chemical Society - Perkin Transactions 1, , # 16 p. 2335 - 2342
反应条件
Arthrobacter atrocyaneus in N,N-dimethyl-formamide T=32°C; 48 h; Microbiological reaction; enantioselective reaction;
参考文献
Journal of Molecular Catalysis B: Enzymatic, , vol. 83, p. 23 - 28
反应条件
(1S,2R)-(+)-N,N-dimethylephedrinium bis(trifluoromethanesulfon)imidate in dichloromethane T=120°C;
参考文献
Analytical Chemistry, , vol. 76, # 22 p. 6819 - 6822
反应条件
dimethylsulfide borane complex; (S)-2-(anilinodiphenylmethyl)pyrrolidine in tetrahydrofuran T=20°C; 2 h; enantioselective reaction;
参考文献
Tetrahedron, , vol. 69, # 6 p. 1739 - 1746
反应条件
Candida antarctica lipase B; (η5-C5Ph5)Ru(CO)2Cl; potassium tert-butylate; sodium carbonate in tetrahydrofuran; toluene T=20°C; 17 h;
参考文献
Journal of the American Chemical Society, , vol. 127, # 24 p. 8817 - 8825
反应条件
titanium(IV) isopropylate; methyl 4,6-O-PhCH-2-deoxy-2-p-TsNH-α-D-glucopyranoside in dichloromethane; toluene T=20°C; 3 h; Product distribution; Further Variations:CatalystsTemperaturesamounts of catalyst; reaction times;
参考文献
Tetrahedron Asymmetry, , vol. 13, # 1 p. 77 - 82
反应条件
1: (1S,3S,4R)-2-benzyl-3-[(1S,4R)-7,7-dimethyl-2-oxobicyclo[2.2.1]hept-1-yl]-2-thioniabicyclo[2.2.1]heptane tetrafluoroborate With lithium hexamethyldisilazane in tetrahydrofuran; dichloromethane T=-78°C; 1 h; 2: triethyl borane in tetrahydrofuran; dichloromethane T=-100 - 0°C; 3: With sodium hydroxide; dihydrogen peroxide in tetrahydrofuran; dichloromethane T=0 - 20°C; Further stages.;
参考文献
Journal of the American Chemical Society, , vol. 129, # 47 p. 14632 - 14639
反应条件
1: diethylzinc; phenylacetylene With (-)-2-exo-morpholinoisobornane-10-thiol in tetrahydrofuran; toluene T=20°C; 2 h; 2: benzaldehyde in tetrahydrofuran; toluene T=0°C; 22 h;
参考文献
US2011/295042 A1, ;
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