N-ALPHA-苄酰-L-精氨酸合成路线 (共 56 条)
反应条件
sodium hydrogencarbonate in N,N-dimethyl-formamide T=20°C; 1 h;
参考文献
Yokohama City University
Patent: EP1717224 A1, 2006 ;
Location in patent: Page/Page column 20-21 ;
反应条件
in tetrahydrofuran; water 4 h; Ambient temperature;
参考文献
Nagao, Yoshimitsu; Miyasaka, Tadayo; Seno, Kaoru; Fujita, Eiichi; Shibata, Daisuke; Doi, Etsushiro
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1984 , p. 2439 - 2446
反应条件
water in N,N-dimethyl-formamide T=35°C; pH 5.0; influence of enzyme papain; influence of BzPheal=Ala; Rate constantEquilibrium constant;
参考文献
Journal of Medicinal Chemistry, , vol. 32, # 6 p. 1253 - 1259
反应条件
1: 1.) DCC / 1.) 1,4-dioxane, 15 min, 2.) 1,4-dioxane, 18 h 2: borate buffer (pH 8.5) / dioxane / 2 h / Ambient temperature View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 35, # 7 p. 1246 - 1259
参考文献
Journal of Biological Chemistry, , vol. 127, p. 643,647
Biochemical Preparations, , vol. 6, p. 61,64
Journal of Biological Chemistry, , vol. 172, p. 221,226-235
反应条件
borate buffer in 1,4-dioxane 2 h; Ambient temperature; Yield given;
参考文献
Journal of Medicinal Chemistry, , vol. 35, # 7 p. 1246 - 1259
反应条件
ethylenediaminetetraacetic acid; water; mercaptoacetic acid in dimethyl sulfoxide papain-cat. hydrolysis (spec. activity); phosphate buffer (pH=8.5);
参考文献
Monatshefte fuer Chemie, , vol. 117, p. 1195 - 1204
反应条件
water T=30°C; Peptidamidase aus dem Flavedo von Orangen; Yield given;
参考文献
Angewandte Chemie, , vol. 102, # 10 p. 1204 - 1206
反应条件
subtilisin BPN' in methanol; water kcat and Km; other cosolvents; pH 8.0; Rate constant;
参考文献
Journal of the American Chemical Society, , vol. 112, # 3 p. 945 - 953
反应条件
hydrogenchloride; borate buffer; sodium chloride; calcium chloride; trypsin in water T=30°C; var. of substrate, amino acid amide, conc.; Product distribution;
参考文献
Pharmazie, , vol. 51, # 10 p. 710 - 714