2-氨基-2-乙基己酸乙酯合成路线 （共 13 条）
反应条件
hydrogenchloride 1 h; Ambient temperature;
参考文献
Liu, Weiguo; Ray, Paul; Benezra, Steven A.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1995 , # 5 p. 553 - 560
反应条件
1: NH4Cl / H2O; ethanol / 48 h / 55 - 60 °C 2: conc. HCl / 24 h / 80 °C 3: H2SO4 / Heating View Scheme
参考文献
Helvetica Chimica Acta, , vol. 83, # 10 p. 2823 - 2835
反应条件
1: 85 percent / lithium diisopropylamine / tetrahydrofuran / 10 h / Ambient temperature 2: 94 percent / aq. HCl / 1 h / Ambient temperature View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 5 p. 553 - 560
反应条件
1: 98 percent / Et3N / toluene / Heating 2: 85 percent / lithium diisopropylamine / tetrahydrofuran / 10 h / Ambient temperature 3: 94 percent / aq. HCl / 1 h / Ambient temperature View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 5 p. 553 - 560
反应条件
1: conc. HCl / 24 h / 80 °C 2: H2SO4 / Heating View Scheme
参考文献
Helvetica Chimica Acta, , vol. 83, # 10 p. 2823 - 2835
反应条件
sulfuric acid Esterification; Heating;
参考文献
Helvetica Chimica Acta, , vol. 83, # 10 p. 2823 - 2835
反应条件
porcine liver esterase in phosphate buffer T=30°C; Hydrolysis; resolution of racemate; pH=8.0; 7.5 h;
参考文献
Imawaka, Naoto; Tanaka, Masakazu; Suemune, Hiroshi
Helvetica Chimica Acta, 2000 , vol. 83, # 10 p. 2823 - 2835
反应条件
phosphate buffer; Humicola amino esterase Ambient temperature;
参考文献
Liu, Weiguo; Ray, Paul; Benezra, Steven A.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1995 , # 5 p. 553 - 560
反应条件
porcine liver esterase in phosphate buffer T=30°C; Hydrolysis; resolution of racemate; pH=8.0; 7.5 h;
参考文献
Imawaka, Naoto; Tanaka, Masakazu; Suemune, Hiroshi
Helvetica Chimica Acta, 2000 , vol. 83, # 10 p. 2823 - 2835
反应条件
water; sodium hydroxide T=20°C; pH=9.4 - 9.8; 28 h;
参考文献
Cowan, David J.; Collins, Jon L.; Mitchell, Mark B.; Ray, John A.; Sutton, Peter W.; Sarjeant, Amy A.; Boros, Eric E.
Journal of Organic Chemistry, 2013 , vol. 78, # 24 p. 12726 - 12734
