5,5-二甲基噻唑烷-4-羧酸合成路线 （共 7 条）
反应条件
in ethanol; water T=20°C; 21 h;
参考文献
Ikunaka, Masaya; Matsumoto, Jun; Nishimoto, Yukifumi
Tetrahedron Asymmetry, 2002 , vol. 13, # 11 p. 1201 - 1208
反应条件
formaldehyd; sodium acetate in hydrogenchloride
参考文献
E. R. Squibb and Sons, Inc.
Patent: US4192878 A1, 1980 ;
US 4192878 A
反应条件
1: diethyl ether 2: aq. HCl / 24 h / Heating View Scheme
参考文献
Asinger,F. et al.
Justus Liebigs Annalen der Chemie, 1966 , vol. 697, p. 140 - 157
反应条件
hydrogenchloride 24 h; Heating;
参考文献
Asinger,F. et al.
Justus Liebigs Annalen der Chemie, 1966 , vol. 697, p. 140 - 157
反应条件
1: diluted aqueous HCl View Scheme
参考文献
Tatsuoka; Miyamoto
Yakugaku Zasshi, 1949 , vol. 69, p. 294,297
Chem.Abstr., 1950 , p. 2513
反应条件
1: sodium; liquid NH3 2: diluted aqueous HCl View Scheme
参考文献
Tatsuoka; Miyamoto
Yakugaku Zasshi, 1949 , vol. 69, p. 294,297
Chem.Abstr., 1950 , p. 2513
反应条件
1.1: 84 percent / HCl / 4 h / Heating 2.1: Klebsiella oxytoca hydrolase / H2O / 26 h / 60 °C 2.2: aq. NaOH / various solvent(s) / pH 11.5 2.3: 23.6 percent / aq. NaOH; propan-2-ol / 4 h / 20 °C View Scheme
参考文献
Ikunaka, Masaya; Matsumoto, Jun; Nishimoto, Yukifumi
Tetrahedron Asymmetry, 2002 , vol. 13, # 11 p. 1201 - 1208
