(R)-1-(4-氯苯基)-1,2-乙二醇合成路线 （共 24 条）
反应条件
hydrogen; chiral iridium(III) complex in methanol T=60°C; P=7600.51 Torr; 15 h;
参考文献
Ohkuma, Takeshi; Utsumi, Noriyuki; Watanabe, Masahito; Tsutsumi, Kunihiko; Arai, Noriyoshi; Murata, Kunihiko
Organic Letters, 2007 , vol. 9, # 13 p. 2564 - 2567
反应条件
mono-AllBr salt of diquinidinyl phthalazine-1,4-diyl ether; 4-methylmorpholine N-oxide; osmium(VIII) oxide in water; tert-butyl alcohol T=20°C; 20 h;
参考文献
Choi, Doo Seung; Han, Sang Seop; Kwueon, Eun Kyung; Choi, Han Young; Hwang, Soon Ho; Park, Yil Sung; Song, Choong Eui
Advanced Synthesis and Catalysis, 2006 , vol. 348, # 18 p. 2560 - 2564
反应条件
(S,S)-[1,2-cyclohexanediamino-N,N'-bis(3,5-di-t-butylsalicylidene)]cobaltIII*OAc; water in tetrahydrofuran T=0 - 20°C; 48 h;
参考文献
Schaus, Scott E.; Brandes, Bridget D.; Larrow, Jay F.; Tokunaga, Makoto; Hansen, Karl B.; Gould, Alexandra E.; Furrow, Michael E.; Jacobsen, Eric N.
Journal of the American Chemical Society, 2002 , vol. 124, # 7 p. 1307 - 1315
反应条件
oxygen in water Pseudomonas putida strain 39D; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Tetrahedron: Asymmetry, , vol. 4, # 6 p. 1365 - 1386
反应条件
1: 4-chlorostyrene oxide With water; (S,S)-[1,2-cyclohexanediamino-N,N'-bis(3,5-di-t-butylsalicylidene)]cobaltIII*OAc in tetrahydrofuran T=0 - 20°C; 16 h; 2: N-Boc-2-nitrobenzenesulfonamide With oxygen in tetrahydrofuran T=20°C; 72 h; Title compound not separated from byproducts;
参考文献
Angewandte Chemie - International Edition, , vol. 43, # 30 p. 3952 - 3954
反应条件
1: copper(I) iodide; triethylamine / PdCl2(PPh3)2 / 100 °C 2: aq. NaOH / methanol / 20 °C 3: HSiCl3 / [PtCl2(C2H4)]2 / 24 h / 20 °C 4: HSiCl3; (R)-2-bis[3,5-bis(CF3)phenyl]phosphino-1,1'-binaphthyl / [PdCl(π-C3H5)]2 / toluene / 72 h / 20 °C 5: ag. H2O2; KF; KHCO3 / tetrahydrofuran; methanol / 50 °C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 124, # 8 p. 1584 - 1585
反应条件
1: HSiCl3 / [PtCl2(C2H4)]2 / 24 h / 20 °C 2: HSiCl3; (R)-2-bis[3,5-bis(CF3)phenyl]phosphino-1,1'-binaphthyl / [PdCl(π-C3H5)]2 / toluene / 72 h / 20 °C 3: ag. H2O2; KF; KHCO3 / tetrahydrofuran; methanol / 50 °C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 124, # 8 p. 1584 - 1585
反应条件
1: aq. NaOH / methanol / 20 °C 2: HSiCl3 / [PtCl2(C2H4)]2 / 24 h / 20 °C 3: HSiCl3; (R)-2-bis[3,5-bis(CF3)phenyl]phosphino-1,1'-binaphthyl / [PdCl(π-C3H5)]2 / toluene / 72 h / 20 °C 4: ag. H2O2; KF; KHCO3 / tetrahydrofuran; methanol / 50 °C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 124, # 8 p. 1584 - 1585
反应条件
(S,S)-[1,2-cyclohexanediamino-N,N'-bis(3,5-di-t-butylsalicylidene)]cobaltIII*OAc; water in tetrahydrofuran T=0 - 20°C; 48 h;
参考文献
Schaus, Scott E.; Brandes, Bridget D.; Larrow, Jay F.; Tokunaga, Makoto; Hansen, Karl B.; Gould, Alexandra E.; Furrow, Michael E.; Jacobsen, Eric N.
Journal of the American Chemical Society, 2002 , vol. 124, # 7 p. 1307 - 1315
反应条件
sodium hydroxide; sodium phosphate buffer; Aspergillus niger epoxide hydrolase T=0°C; pH=7; KineticsProduct distribution; Further Variations:Reagents;
参考文献
Tetrahedron, , vol. 57, # 4 p. 695 - 701
