(S)-(+)-1-苯基-2-丙醇合成路线 （共 70 条）
反应条件
(i) PBr5, CHCl3, (ii) Zn-Cu, aq. HCl; Multistep reaction;
参考文献
Chemische Berichte, , vol. 94, p. 893 - 901
反应条件
water T=30°C; 168 h; asymmetric hydrolysis and resolution by Pseudomonas cepacia; Product distribution;
参考文献
Bioscience, Biotechnology, and Biochemistry, , vol. 58, # 7 p. 1330 - 1331
反应条件
sodium nitrite in perchloric acid; water Product distributionMechanism;
参考文献
Chemische Berichte, , vol. 113, # 6 p. 2140 - 2153
反应条件
potassium hydroxide; RuCl(η5-C9H7)(PPh3)2 in dichloromethane T=25°C; 3.5 h;
参考文献
Csjernyik, Gabor; Bogar, Krisztian; Baeckvall, Jan-E.
Tetrahedron Letters, 2004 , vol. 45, # 36 p. 6799 - 6802
反应条件
NADH-H+; nicotinamide adenine dinucleotide; RE-ADH/LK-ADH in phosphate buffer T=30°C; 24 h;
参考文献
Chemistry - A European Journal, , vol. 13, # 29 p. 8271 - 8276
反应条件
1: triethylamine / CH2Cl2 / 0.5 h / 0 °C 2: 0.37 g / sodium azide / dimethylformamide / 6 h / 80 °C 3: 98 percent / hydrogen / Pd/C / methanol / 2 h / 760.05 Torr 4: 95 percent / triethylamine / CH2Cl2 / 1 h / 0 °C 5: 92 percent / LiAlH4 / tetrahydrofuran / 4 h / Heating 6: 72 percent / anhydrous potassium carbonate / acetonitrile / 12 h / 25 °C View Scheme
参考文献
Tetrahedron, , vol. 63, # 39 p. 9758 - 9763
反应条件
1: triethylamine / CH2Cl2 / 0.5 h / 0 °C 2: 0.37 g / sodium azide / dimethylformamide / 6 h / 80 °C 3: 98 percent / hydrogen / Pd/C / methanol / 2 h / 760.05 Torr 4: 95 percent / triethylamine / CH2Cl2 / 1 h / 0 °C 5: 92 percent / LiAlH4 / tetrahydrofuran / 4 h / Heating View Scheme
参考文献
Kondekar, Nagendra B.; Kumar, Pradeep
Synthetic Communications, 2011 , vol. 41, # 9 p. 1301 - 1308
反应条件
1: 85 percent / 4-(dimethylamino)pyridine; pyridine / 3 h / 30 °C 2: triethylamine / 3 h / 75 - 80 °C 3: aq. LiOH / methanol / 3 h / 20 °C View Scheme
参考文献
Musa, Musa M.; Phillips, Robert S.; Laivenieks, Maris; Vieille, Claire; Takahashi, Masateru; Hamdan, Samir M.
Organic and Biomolecular Chemistry, 2013 , vol. 11, # 17 p. 2911 - 2915
反应条件
1: triethylamine / CH2Cl2 / 0.5 h / 0 °C 2: 0.37 g / sodium azide / dimethylformamide / 6 h / 80 °C 3: 98 percent / hydrogen / Pd/C / methanol / 2 h / 760.05 Torr 4: 95 percent / triethylamine / CH2Cl2 / 1 h / 0 °C 5: 92 percent / LiAlH4 / tetrahydrofuran / 4 h / Heating 6: 72 percent / anhydrous potassium carbonate / acetonitrile / 12 h / 25 °C View Scheme
参考文献
Tetrahedron, , vol. 63, # 39 p. 9758 - 9763
反应条件
oxygen; H218O in gaseous matrix
T=25°C; Irradiationother temperatures; Product distributionKineticsMechanism;
参考文献
Speranza, Maurizio; Filippi, Antonello
Chemistry - A European Journal, 1999 , vol. 5, # 3 p. 834 - 844
