2-氯-2,2-二氟乙酸甲酯合成路线 （共 95 条）
反应条件
potassium fluoride; copper(l) iodide in N,N-dimethyl-formamide
T=120°C; 8 h; Product distributionMechanism;
参考文献
Su, De-Bao; Duan, Jian-Xing; Yu, An-Juan; Chen, Qing-Yun
Journal of Fluorine Chemistry, 1993 , vol. 65, # 1-2 p. 11 - 14
反应条件
potassium fluoride; copper(l) iodide in N,N-dimethyl-formamide
T=100°C; 8 h; Yield given;
参考文献
Duan, Jian-Xing; Su, De-Bao; Wu, Jian-Ping; Chen, Qing-Yun
Journal of Fluorine Chemistry, 1994 , vol. 66, # 2 p. 167 - 170
反应条件
potassium fluoride; copper(l) iodide in N,N-dimethyl-formamide
T=120°C; 8 h; also with bromobenzene; further times and temperatures for methyl bromodifluoroacetates; Product distributionMechanism;
参考文献
Su, De-Bao; Duan, Jian-Xing; Yu, An-Juan; Chen, Qing-Yun
Journal of Fluorine Chemistry, 1993 , vol. 65, # 1-2 p. 11 - 14
反应条件
RuHCl(CO)(bis-(2-diphenylphosphinoethyl)amine); hydrogen; sodium methylate in methanol
T=40°C; P=7600.51 Torr; 22 h; AutoclaveInert atmosphere;
参考文献
Central Glass Company, Limited; ISHII, Akihiro; OOTSUKA, Takashi; IMAMURA, Mari; NISHIMIYA, Takayuki; KIMURA, Kazuto
Patent: EP2740719 A1, 2014 ;
Location in patent: Paragraph 0056 ;
反应条件
potassium fluoride; copper(l) chloride in N,N-dimethyl-formamide
T=120°C; 12 h;
参考文献
DOW AGROSCIENCES LLC
Patent: US2011/301178 A1, 2011 ;
Location in patent: Page/Page column 8 ;
反应条件
potassium fluoride; copper(l) iodide in N,N-dimethyl-formamide
T=115°C; 5 h;
参考文献
NIHON NOHYAKU CO., LTD.
Patent: EP1757595 A1, 2007 ;
Location in patent: Page/Page column 24 ;
反应条件
sodium methylate in diethyl ether
参考文献
Moore,R.A.; Levine,R.
Journal of Organic Chemistry, 1964 , vol. 29, p. 1439 - 1444
反应条件
potassium fluoride; copper(l) iodide in N,N-dimethyl-formamide
T=120°C;
参考文献
Brotherton-Pleiss, Christine E.; Caroon, Joan Marie; Lopez-Tapia, Francisco Javier
Patent: US2010/160388 A1, 2010 ;
Location in patent: Page/Page column 64-65 ;
US 20100160388 A1
反应条件
potassium fluoride; copper(l) iodide; cadmium (II) iodide in N,N,N',N',N'',N''-hexamethylphosphoric triamide
T=120°C; 8 h;
参考文献
Chen, Qing-Yun; Duan, Jian-Xing
Tetrahedron Letters, 1993 , vol. 34, # 26 p. 4241 - 4244
反应条件
RuHCl(CO)(bis-(2-diphenylphosphinoethyl)amine); hydrogen; sodium methylate in methanol
T=40°C; P=7600.51 Torr; 22 h; AutoclaveInert atmosphere;
参考文献
Central Glass Company, Limited; ISHII, Akihiro; OOTSUKA, Takashi; IMAMURA, Mari; NISHIMIYA, Takayuki; KIMURA, Kazuto
Patent: EP2740719 A1, 2014 ;
Location in patent: Paragraph 0056 ;
