3-环己烯-1-羧酸乙酯合成路线 （共 19 条）
反应条件
1,8-diazabicyclo[5.4.0]undec-7-ene in N,N-dimethyl-formamide T=20 - 120°C; 18 h;
参考文献
EP2368870 A1, ;
Page/Page column 13 ;
EP 2368870 A1
反应条件
erbium trifluoromethanesulfonate T=20°C; Diels-Alder reaction; 3 h; Ionic liquid; regioselective reaction;
参考文献
Bortolini, Olga; De Nino, Antonio; Garofalo, Angelo; Maiuolo, Loredana; Procopio, Antonio; Russo, Beatrice
Applied Catalysis A: General, 2010 , vol. 372, # 2 p. 124 - 129
反应条件
1: allenylmethyl bromide With indium in N,N-dimethyl-formamide T=20°C; 0.5 h; Inert atmosphere; 2: ethyl acrylate in N,N-dimethyl-formamide T=80°C; Diels-Alder reaction; 2 h; Inert atmosphere; 3: With water; sodium hydrogencarbonate in N,N-dimethyl-formamide Inert atmosphere;
参考文献
Mo, Juntae; Kim, Sung Hong; Lee, Phil Ho
Organic Letters, 2010 , vol. 12, # 3 p. 424 - 427
反应条件
1: oxalyl chloride / toluene / 18 h / Ambient temperature 2: toluene / 18 h / Ambient temperature View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 34, # 8 p. 2484 - 2488
反应条件
1: hydrogenchloride / water / 6 h / 20 °C / Reflux 2: 1,8-diazabicyclo[5.4.0]undec-7-ene / N,N-dimethyl-formamide / 18 h / 20 - 120 °C View Scheme
参考文献
EP2368870 A1, ;
EP 2368870 A1
反应条件
in toluene 18 h; Ambient temperature; Yield given;
参考文献
Journal of Medicinal Chemistry, , vol. 34, # 8 p. 2484 - 2488
反应条件
methyl-magnesium iodide
参考文献
Journal of Organic Chemistry USSR (English Translation), , vol. 7, p. 945 - 949
Zhurnal Organicheskoi Khimii, , vol. 7, # 5 p. 929 - 935
参考文献
Zhurnal Obshchei Khimii, , vol. 8, p. 460,470
Chem. Zentralbl., , vol. 110, # II p. 632
反应条件
1: MeMgI View Scheme
参考文献
Journal of Organic Chemistry USSR (English Translation), , vol. 7, p. 945 - 949
Zhurnal Organicheskoi Khimii, , vol. 7, # 5 p. 929 - 935
反应条件
in water; acetic acid
参考文献
Journal of the Chemical Society, , p. 410 - 421
