6-甲氧基-2-吲哚羧酸乙酯合成路线 （共 7 条）
反应条件
dirhodium tetraacetate in toluene Inert atmosphereReflux;
参考文献
Wang, Rui; Shi, Hong-Fan; Zhao, Jing-Feng; He, Yan-Ping; Zhang, Hong-Bin; Liu, Jian-Ping
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 6 p. 1760 - 1762
反应条件
tetrabutylammomium bromide; palladium diacetate; sodium hydrogencarbonate in acetonitrile T=80°C; Heck-Jeffery amination; 96 h; Inert atmosphere;
参考文献
McNulty, James; Keskar, Kunal
European Journal of Organic Chemistry, 2011 , # 34 p. 6902 - 6908
反应条件
1: 70 percent / 5 h / 90 °C 2: 68 percent / ZnCl2 / CH2Cl2 / 24 h / 20 °C View Scheme
参考文献
Synlett, , # 5 p. 749 - 755
反应条件
1: K2CO3 / acetone / 12 h / 60 °C 2: 70 percent / 5 h / 90 °C 3: 68 percent / ZnCl2 / CH2Cl2 / 24 h / 20 °C View Scheme
参考文献
Synlett, , # 5 p. 749 - 755
反应条件
1: sodium ethanolate / ethanol / 13.5 h / -5 - 0 °C 2: dirhodium tetraacetate / toluene / |Inert atmosphere; |Reflux View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 23, # 6 p. 1760 - 1762
参考文献
Gazzetta Chimica Italiana, , vol. 88, p. 574,589
反应条件
lithium hydroxide in tetrahydrofuran; water
参考文献
JANSSEN PHARMACEUTICA, N.V.
Patent: WO2004/22061 A1, 2004 ;
Location in patent: Page/Page column 71 ;
WO 2004/022061 A1
