3-(3,4,5-三甲氧基苯基)-2-丙烯-1-醇合成路线 （共 16 条）
反应条件
1: With lithium aluminium tetrahydride in tetrahydrofuran T=20°C; 6 h; 2: in tetrahydrofuran; water T=10 - 15°C; pH=5; Acidic aqueous solution;
参考文献
Spangler, Brenda D.; Spangler, Charles W.; Tarter, E. Scott
Patent: US2009/43109 A1, 2009 ;
Location in patent: Page/Page column sheet 4; 11 ;
反应条件
diisobutylaluminium hydride in hexane; dichloromethane T=-15°C; 1 h;
参考文献
Sampath Kumar; Tiwari, Ashok K.; Venkat Reddy; Aparna; Jagadeeshwar Rao; Zehra Ali; Madhusudana Rao
Journal of Natural Products, 2005 , vol. 68, # 11 p. 1615 - 1621
反应条件
diisobutylaluminium hydride in dichloromethane; toluene T=-78°C; 1.5 h;
参考文献
Bourdron, Julien; Commeiras, Laurent; Barbier, Pascale; Bourgarel-Rey, Veronique; Pasquier, Eddy; Vanthuyne, Nicolas; Hubaud, Jean-Claude; Peyrot, Vincent; Parrain, Jean-Luc
Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 16 p. 5540 - 5548
反应条件
lithium aluminium tetrahydride in tetrahydrofuran 2 h; Ambient temperature;
参考文献
Hu, Li Hong; Zou, Hong Bin; Gong, Jing Xu; Li, Hai Bo; Yang, Lei Xiang; Cheng, Wei; Zhou, Chang Xin; Bai, Hua; Gueritte, Francoise; Zhao, Yu
Journal of Natural Products, 2005 , vol. 68, # 3 p. 342 - 348
反应条件
diisobutylaluminium hydride in tetrahydrofuran; methanol; hexane
参考文献
SUMITOMO PHARMACEUTICALS COMPANY, LIMITED
Patent: EP801071 A1, 1997 ;
反应条件
hydrogenchloride; sodium borohydride; triethylamine in tetrahydrofuran
参考文献
Kowa Co., Ltd.
Patent: US2003/22887 A1, 2003 ;
反应条件
1: piperidine; pyridine / Heating 2: LAH / tetrahydrofuran / 20 °C View Scheme
参考文献
Cooper,P.D.
Canadian Journal of Chemistry, 1970 , vol. 48, p. 3882 - 3888
反应条件
1: triethylbenzylammonium chloride, 45 percent NaOH / H2O; CHCl3 / 5 h / Heating 2: LiAlH4 / diethyl ether / 2 h / Heating View Scheme
参考文献
Ehret, Charles; Maupetit, Pierre
Phytochemistry (Elsevier), 1982 , vol. 21, # 12 p. 2984 - 2985
反应条件
1: hydrogen; C21H10F12NOP; [rhodium(I)(carbonyl)2(acetylacetonate)] / toluene / 20 h / 55 °C / 3750.38 Torr 2: sodium tetrahydroborate; cerium(III) chloride / methanol; dichloromethane / 1.5 h / 0 °C View Scheme
参考文献
Agabekov, Vladislav; Seiche, Wolfgang; Breit, Bernhard
Chemical Science, 2013 , vol. 4, # 6 p. 2418 - 2422
反应条件
1: Pd2(PPh3)2Cl2; copper(l) iodide; N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 1 h / 20 °C 2: potassium carbonate / methanol / 3 h / 20 °C 3: hydrogen; C21H10F12NOP; [rhodium(I)(carbonyl)2(acetylacetonate)] / toluene / 20 h / 55 °C / 3750.38 Torr 4: sodium tetrahydroborate; cerium(III) chloride / methanol; dichloromethane / 1.5 h / 0 °C View Scheme
参考文献
Agabekov, Vladislav; Seiche, Wolfgang; Breit, Bernhard
Chemical Science, 2013 , vol. 4, # 6 p. 2418 - 2422
