(’±)-2-苯基环庚酮合成路线 （共 37 条）
反应条件
2: platinum; ethanol / Hydrogenation
View Scheme
参考文献
Doering,von E.; Hiskey
Journal of the American Chemical Society, 1952 , vol. 74, p. 5688,5693
反应条件
2: platinum; ethanol / Hydrogenation
View Scheme
参考文献
Doering,von E.; Hiskey
Journal of the American Chemical Society, 1952 , vol. 74, p. 5688,5693
反应条件
methanol; potassium carbonate
Nebenprod. 2: 3-Phenyl-cycloheptanon;
参考文献
Gutsche
Journal of the American Chemical Society, 1949 , vol. 71, p. 3513,3515
反应条件
iron tribromide in toluene
T=80°C; Wagner-Meerwein Rearrangement; 14 h; Inert atmosphereSchlenk techniqueSealed tube; chemoselective reaction;
参考文献
Gutierrez-Bonet, Alvaro; Flores-Gaspar, Areli; Martin, Ruben
Journal of the American Chemical Society, 2013 , vol. 135, # 34 p. 12576 - 12579
反应条件
boron trifluoride diethyl etherate in water; acetone
参考文献
Sacks,C.E.; Fuchs,P.L.
Synthesis, 1976 , p. 456 - 457
反应条件
tetraethylammonium chloride in dichloromethane
electrolysis;
参考文献
Kimura, Makoto; Kobayashi, Kazutaka; Yamamoto, Yasushi; Sawaki, Yasuhiko
Tetrahedron, 1996 , vol. 52, # 12 p. 4303 - 4310
反应条件
1: CuBr*Me2S / tetrahydrofuran / 0 °C
2: aq. Dess-Martin periodinane / CH2Cl2 / 20 °C
View Scheme
参考文献
Pinard, Emmanuel; Ceccarelli, Simona M.; Stalder, Henri; Alberati, Daniela
Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 2 p. 349 - 353
反应条件
sodium methylate in methanol
Heating; Yield given. Yields of byproduct given;
参考文献
Gokhale, Abha; Schiess, Peter
Helvetica Chimica Acta, 1998 , vol. 81, # 2 p. 251 - 267
反应条件
1.1: N-chloro-succinimide / tetrachloromethane / 15 h / 20 °C
2.1: lithium diisopropyl amide / tetrahydrofuran / Inert atmosphere; Cooling
2.2: Inert atmosphere; Cooling
3.1: 1,1-dimethylethylmagnesium chloride / tetrahydrofuran / -45 °C / Inert atmosphere
3.2: -45 - 20 °C / Inert atmosphere
View Scheme
参考文献
Fukuda, Shigehiko; Tsuji, Kazuhito; Musashi, Jun; Nonaka, Ryo; Kimura, Tsutomu; Satoh, Tsuyoshi
Synthesis, 2011 , # 22 art. no. F71511SS, p. 3615 - 3626
反应条件
1.1: lithium diisopropyl amide / tetrahydrofuran / Inert atmosphere; Cooling
1.2: Inert atmosphere; Cooling
2.1: 1,1-dimethylethylmagnesium chloride / tetrahydrofuran / -45 °C / Inert atmosphere
2.2: -45 - 20 °C / Inert atmosphere
View Scheme
参考文献
Fukuda, Shigehiko; Tsuji, Kazuhito; Musashi, Jun; Nonaka, Ryo; Kimura, Tsutomu; Satoh, Tsuyoshi
Synthesis, 2011 , # 22 art. no. F71511SS, p. 3615 - 3626
