3-甲基-3,4-二氢-2H-萘-1-酮合成路线 （共 34 条）
反应条件
PPA 1.) 95-100 deg C; 2.) 105-115 deg C, 2 h; 3.) rt, 8 h;
参考文献
Verbel, Joel; Carrie, Robert
Bulletin de la Societe Chimique de France, 1982 , vol. 2, # 3-4 p. 116 - 124
反应条件
sodium chloride in dimethyl sulfoxide T=200°C;
参考文献
Roy; Rahman; Islam
Journal of Chemical Research - Part S, 2003 , # 9 p. 594 - 596
反应条件
sulfuric acid T=100°C; 8 h;
参考文献
Katsuura, K.; Snieckus, V.
Canadian Journal of Chemistry, 1987 , vol. 65, p. 124 - 130
反应条件
1: 92 percent / KOH / ethane-1,2-diol; H2O / Heating 2: 95 percent / polyphosphoric acid / 1.) 95-100 deg C; 2.) 105-115 deg C, 2 h; 3.) rt, 8 h View Scheme
参考文献
Cui, Li-Qian; Dong, Zhi-Lei; Liu, Kai; Zhang, Chi
Organic Letters, 2011 , vol. 13, # 24 p. 6488 - 6491
反应条件
1: With [(η2-cyclooctene)4Rh2(μ-Cl)2]; 3-methyl-5-(pyrrolidin-1-yl)pyridin-2-amine; aniline; triphenylphosphine; benzoic acid in 2,3,4-trifluorotoluene T=100°C; 36 h; Inert atmosphere; 2: With hydrogenchloride in dichloromethane; water; 2,3,4-trifluorotoluene 0.166667 h;
参考文献
Beletskiy, Evgeny V.; Sudheer; Douglas, Christopher J.
Journal of Organic Chemistry, 2012 , vol. 77, # 14 p. 5884 - 5893
反应条件
1: 84 percent / acetic acid, ammonium acetate / benzene / 6 h / Heating 2: 95 percent / H2 / 5percent Pd/C / aq. ethanol / 2 h / 760 Torr / Ambient temperature 3: 92 percent / KOH / ethane-1,2-diol; H2O / Heating 4: 95 percent / polyphosphoric acid / 1.) 95-100 deg C; 2.) 105-115 deg C, 2 h; 3.) rt, 8 h View Scheme
参考文献
Cui, Li-Qian; Dong, Zhi-Lei; Liu, Kai; Zhang, Chi
Organic Letters, 2011 , vol. 13, # 24 p. 6488 - 6491
反应条件
1: palladium 10 on activated carbon; hydrogen 2: water; potassium hydroxide / ethanol / 24 h / Reflux 3: trifluorormethanesulfonic acid / 5 h / 20 °C View Scheme
参考文献
Cui, Li-Qian; Dong, Zhi-Lei; Liu, Kai; Zhang, Chi
Organic Letters, 2011 , vol. 13, # 24 p. 6488 - 6491
反应条件
1: H2 / 5percent Pd/C / aq. ethanol / 13 h / 760 Torr / Ambient temperature 2: 1.) acetic acid, cc. H2SO4; 2.) acetic acid, cc. H2SO4 / H2O / 1.) 20 h, reflux; 2.) 6 h, reflux 3: 95 percent / polyphosphoric acid / 1.) 95-100 deg C; 2.) 105-115 deg C, 2 h; 3.) rt, 8 h View Scheme
参考文献
Verbel, Joel; Carrie, Robert
Bulletin de la Societe Chimique de France, 1982 , vol. 2, # 3-4 p. 116 - 124
反应条件
1: 95 percent / H2 / 5percent Pd/C / aq. ethanol / 2 h / 760 Torr / Ambient temperature 2: 92 percent / KOH / ethane-1,2-diol; H2O / Heating 3: 95 percent / polyphosphoric acid / 1.) 95-100 deg C; 2.) 105-115 deg C, 2 h; 3.) rt, 8 h View Scheme
参考文献
Verbel, Joel; Carrie, Robert
Bulletin de la Societe Chimique de France, 1982 , vol. 2, # 3-4 p. 116 - 124
反应条件
1: 78 percent / n-BuLi / tetrahydrofuran / 1 h / -78 °C 2: 10.10 g / Raney-Ni / aq. ethanol / 2 h / Heating 3: 79 percent / 75percent H2SO4 / 8 h / 100 °C View Scheme
参考文献
Katsuura, K.; Snieckus, V.
Tetrahedron Letters, 1985 , vol. 26, # 1 p. 9 - 12
