2-氨基-6-氯-9H-嘌呤-9-乙酸合成路线 （共 3 条）
反应条件
potassium carbonate in N,N-dimethyl-formamide 20 h;
参考文献
Dueholm, Kim L.; Egholm, Michael; Behrens, Carsten; Christensen, Leif; Hansen, Henrik F.; et al.
Journal of Organic Chemistry, 1994 , vol. 59, # 19 p. 5767 - 5773
反应条件
lithium hydroxide in 1,4-dioxane; water T=20°C; 4 h;
参考文献
Schwergold, Caroline; Depecker, Geoffrey; Giorgio, Christophe Di; Patino, Nadia; Jossinet, Fabrice; Ehresmann, Bernard; Terreux, Raphael; Cabrol-Bass, Daniel; Condom, Roger
Tetrahedron, 2002 , vol. 58, # 28 p. 5675 - 5687
反应条件
1: 83 percent / NaH / dimethylformamide / 24 h / 0 - 20 °C 2: 71 percent / LiOH / dioxane; H2O / 4 h / 20 °C View Scheme
参考文献
Stefan, Loic; Guedin, Aurore; Amrane, Samir; Smith, Nicole; Denat, Franck; Mergny, Jean-Louis; Monchaud, David
Chemical Communications, 2011 , vol. 47, # 17 p. 4992 - 4994
