3-苯基-4-羟基喹啉-2(1H)-酮合成路线 （共 29 条）
反应条件
copper(l) iodide; caesium carbonate; ethylenediamine in toluene T=110°C; 24 h; Inert atmosphereSealed tube;
参考文献
Fu, Liangbing; Huang, Xiaoli; Wang, Deping; Zhao, Pinghua; Ding, Ke
Synthesis, 2011 , # 10 art. no. H19211SS, p. 1547 - 1554
参考文献
Kafka, Stanislav; Proisl, Karel; Kasparkova, Vera; Urankar, Damijana; Kimmel, Roman; Kosmrlj, Janez
Tetrahedron, 2013 , vol. 69, # 51 p. 10826 - 10835
反应条件
silver nitrate; 1,8-diazabicyclo[5.4.0]undec-7-ene in dimethyl sulfoxide T=60°C; P=750.075 Torr; 24 h; Schlenk technique; Catalytic behavior; Reagent/catalystSolventPressureTime;
参考文献
Ishida, Tomonobu; Kikuchi, Satoshi; Yamada, Tohru
Organic Letters, 2013 , vol. 15, # 14 p. 3710 - 3713
反应条件
1) 220 deg C - 250 deg C, 1 h, 2) 300 deg C;
参考文献
Kimmel, Roman; Kafka, Stanislav; Kosmrlj, Janez
Carbohydrate Research, 2010 , vol. 345, # 6 p. 768 - 779
反应条件
sodium ethanolate in ethanol 5 h; Heating; Yield given;
参考文献
Kulkarni, Bheemashankar A.; Ganesan
Chemical Communications, 1998 , # 7 p. 785 - 786
反应条件
N,N-dimethyl-aniline in acetic acid 4.5 h; Reflux;
参考文献
Rudolf, Ondrej; Mrkvicka, Vladimir; Lycka, Antonin; Rouchal, Michal; Klasek, Antonin
Journal of Heterocyclic Chemistry, 2013 , vol. 50, # SUPPL.1 p. E100-E110
反应条件
1: Na2CO3, H2O / CH2Cl2 / 0.5 h / Ambient temperature 2: 1.) Amberlyst A-26 (OH(-) form), 2.) TFA / 1.) MeOH, r.t., 16 h, 2.) MeOH, r.t., 30 min View Scheme
参考文献
Bezuglyi, P. A.; Ukrainets, I. V.; Treskach, V. I.; Turoy, A. V.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1992 , vol. 28, # 4 p. 438 - 439
Khimiya Geterotsiklicheskikh Soedinenii, 1992 , # 4 p. 522 - 524
反应条件
1: Na2CO3, H2O / CH2Cl2 / 0.5 h / Ambient temperature 2: 1.) Amberlyst A-26 (OH(-) form), 2.) TFA / 1.) MeOH, r.t., 16 h, 2.) MeOH, r.t., 30 min View Scheme
参考文献
Bezuglyi, P. A.; Ukrainets, I. V.; Treskach, V. I.; Turoy, A. V.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1992 , vol. 28, # 4 p. 438 - 439
Khimiya Geterotsiklicheskikh Soedinenii, 1992 , # 4 p. 522 - 524
反应条件
1: triethylamine; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide / tetrahydrofuran / 20 °C / |Inert atmosphere 2: silver nitrate; 1,8-diazabicyclo[5.4.0]undec-7-ene / dimethyl sulfoxide / 24 h / 60 °C / 750.08 Torr / |Schlenk technique View Scheme
参考文献
Ishida, Tomonobu; Kikuchi, Satoshi; Yamada, Tohru
Organic Letters, 2013 , vol. 15, # 14 p. 3710 - 3713
反应条件
1: triethylamine; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide / tetrahydrofuran / 20 °C / |Inert atmosphere 2: silver nitrate; 1,8-diazabicyclo[5.4.0]undec-7-ene / dimethyl sulfoxide / 24 h / 60 °C / 750.08 Torr / |Schlenk technique View Scheme
参考文献
Ishida, Tomonobu; Kikuchi, Satoshi; Yamada, Tohru
Organic Letters, 2013 , vol. 15, # 14 p. 3710 - 3713
