(4-氧代-3(4H)-喹唑啉基)乙酸合成路线 （共 11 条）
反应条件
potassium carbonate; sodium iodide in acetone 24 h; Reflux;
参考文献
Spulak, Marcel; Pourova, Jana; Voprsalova, Marie; Mikusek, Jiri; Kunes, Jiri; Vacek, Jan; Ghavre, Mukund; Gathergood, Nicholas; Pour, Milan
European Journal of Medicinal Chemistry, 2014 , vol. 74, p. 65 - 72
反应条件
potassium carbonate; sodium iodide in acetone 24 h; Reflux;
参考文献
Spulak, Marcel; Novak, Zdenek; Palat, Karel; Kunes, Jiri; Pourova, Jana; Pour, Milan
Tetrahedron, 2013 , vol. 69, # 6 p. 1705 - 1711
反应条件
sodium hydroxide in tetrahydrofuran; methanol 1 h;
参考文献
Escalante, Jaime; Flores, Patricia; Priego, Jaime M.
Heterocycles, 2004 , vol. 63, # 9 p. 2019 - 2032
参考文献
Susse; Johne
Helvetica Chimica Acta, 1985 , vol. 68, # 4 p. 892 - 899
反应条件
1: Et3N / H2O / 1 h / 30 - 40 °C 2: Heating View Scheme
参考文献
Helvetica Chimica Acta, , vol. 68, # 4 p. 892 - 899
反应条件
1: 77 percent / p-toluenesulfonic acid monohydrate / toluene / 2 h / 40 °C 2: 86 percent / aq. sodium hydroxide / tetrahydrofuran; methanol / 1 h View Scheme
参考文献
Heterocycles, , vol. 63, # 9 p. 2019 - 2032
反应条件
potassium permanganate
参考文献
Journal of Organic Chemistry, , vol. 17, p. 19,20
反应条件
1: 6 h / Heating 2: 88 percent View Scheme
参考文献
Helvetica Chimica Acta, , vol. 68, # 4 p. 892 - 899
反应条件
Heating; Yield given;
参考文献
Helvetica Chimica Acta, , vol. 68, # 4 p. 892 - 899
参考文献
Hutchings et al.
Journal of Organic Chemistry, 1952 , vol. 17, p. 19,20
