1-苯磺酰基-7-甲氧基-1H-吲哚合成路线 （共 5 条）
反应条件
sodium hydroxide; tetra(n-butyl)ammonium hydrogensulfate in dichloromethane T=5 - 10°C; 4 h;
参考文献
Gourdoupis; Stamos
Synthetic Communications, 1994 , vol. 24, # 8 p. 1137 - 1144
反应条件
1: 7-methoxy-indole With sodium hydride in N,N-dimethyl-formamide T=0 - 20°C; 1 h; 2: benzenesulfonyl chloride in N,N-dimethyl-formamide T=20°C; 2 h;
参考文献
SYNTA PHARMACEUTICALS CORP.
Patent: WO2008/21364 A2, 2008 ;
Location in patent: Page/Page column 139 ;
反应条件
sulfuric acid 3.5 h; Heating;
参考文献
Fuji; Muratake; Natsume
Chemical and Pharmaceutical Bulletin, 1992 , vol. 40, # 9 p. 2344 - 2352
反应条件
1: 97 percent / tetrahydrofuran / 0.17 h / -20 °C 2: 81 percent / MnO2 / CH2Cl2 / 7 h / Ambient temperature 3: 69 percent / 6percent methanolic H2SO4 / 3.5 h / Heating View Scheme
参考文献
Fuji; Muratake; Natsume
Chemical and Pharmaceutical Bulletin, 1992 , vol. 40, # 9 p. 2344 - 2352
反应条件
1: 81 percent / MnO2 / CH2Cl2 / 7 h / Ambient temperature 2: 69 percent / 6percent methanolic H2SO4 / 3.5 h / Heating View Scheme
参考文献
Fuji; Muratake; Natsume
Chemical and Pharmaceutical Bulletin, 1992 , vol. 40, # 9 p. 2344 - 2352
