5,6,11,12-四氢二苯并[a,e]环辛烯合成路线 （共 46 条）
反应条件
magnesium
T=600°C; P=0.01 - 0.1 Torr; Further byproducts given;
参考文献
Aitken, R. Alan; Hodgson, Philip K.G.; Morrison, John J.; Oyewale, Adebayo O.
Journal of the Chemical Society. Perkin Transactions 1, 2002 , # 3 p. 402 - 415
反应条件
chloranil in benzene
0.5 h;
参考文献
Roth, Wolfgang R.; Biermann, Manfred; Erker, Gerhard; Jelich, Klaus; Gerhartz, Wolfgang; Goerner, Helmut
Chemische Berichte, 1980 , vol. 113, # 2 p. 586 - 597
反应条件
(i) Ag2O, H2O, (ii) (pyrolysis); Multistep reaction;
参考文献
Errede,L.A.
Journal of the American Chemical Society, 1961 , vol. 83, p. 949 - 954
反应条件
n-butyllithium; potassium tert-butylate; iodine
1.) hexane, reflux, 1 h, 2.) THF, from -78 deg C to 20 deg C; Yield given. Multistep reaction;
参考文献
Bates, Robert B.; Ogle, Craig A.
Journal of Organic Chemistry, 1982 , vol. 47, # 20 p. 3949 - 3952
反应条件
tetrabutyl ammonium fluoride in acetonitrile-D3
flow rate: 45 mL/min;
参考文献
Trahanovsky, Walter S.; Chou, C. -H.; Fischer, D. R.; Gerstein, B. C.
Journal of the American Chemical Society, 1988 , vol. 110, # 19 p. 6579 - 6581
反应条件
1: lithium aluminium tetrahydride / tetrahydrofuran / 15 h / Reflux
2: phosphorus tribromide / dichloromethane / 2 h / 20 °C
3: lithium / tetrahydrofuran / 3 h / 20 °C / Inert atmosphere; Sonication
View Scheme
参考文献
Hamza, Abdulhamid
Structural Chemistry, 2010 , vol. 21, # 4 p. 787 - 793
反应条件
1: phosphorus tribromide / dichloromethane / 2 h / 20 °C
2: lithium / tetrahydrofuran / 3 h / 20 °C / Inert atmosphere; Sonication
View Scheme
参考文献
Hamza, Abdulhamid
Structural Chemistry, 2010 , vol. 21, # 4 p. 787 - 793
反应条件
P=117681 Torr; Hydrogenation;
参考文献
Fieser; Pechet
Journal of the American Chemical Society, 1946 , vol. 68, p. 2577,2579
参考文献
Cava; Deana
Journal of the American Chemical Society, 1959 , vol. 81, p. 4266
参考文献
Kloster-Jensen,E.; Wirz,J.
Helvetica Chimica Acta, 1975 , vol. 58, p. 162 - 177
