DL-天冬氨酸二甲酯盐酸盐合成路线 (共 3 条)
反应条件
in methanol T=20°C; 16 h; Cooling with ice; enantioselective reaction;
参考文献
Weber, Frauke; Brune, Stefanie; Korpis, Katharina; Bednarski, Patrick J.; Laurini, Erik; Dal Col, Valentina; Pricl, Sabrina; Schepmann, Dirk; Wuensch, Bernhard
Journal of Medicinal Chemistry, 2014 , vol. 57, # 7 p. 2884 - 2894
参考文献
Colombo, Raffaele; Mingozzi, Michele; Belvisi, Laura; Arosio, Daniela; Piarulli, Umberto; Carenini, Nives; Perego, Paola; Zaffaroni, Nadia; De Cesare, Michelandrea; Castiglioni, Vittoria; Scanziani, Eugenio; Gennari, Cesare
Journal of Medicinal Chemistry, 2012 , vol. 55, # 23 p. 10460 - 10474
反应条件
e.e. = 95percent; Multistep reaction. Title compound not separated from byproducts;
参考文献
Feenstra, R. W.; Stokkingreef, E. H. M.; Nivard, R. J. F.; Ottenheijm, H. C. J.
Tetrahedron Letters, 1987 , vol. 28, # 11 p. 1215 - 1218