(2R)-乙酰氨基-2-苯乙酸合成路线 (共 21 条)
反应条件
LiBr*H2O; sulfuric acid; palladium (II) bromide T=80°C; 12 h; Ionic liquid;
参考文献
Zhao, Qing-Lu; Yang, Min; Wang, Lai-Lai
Synthetic Communications, 2008 , vol. 38, # 24 p. 4460 - 4473
参考文献
Touet, Joel; Faveriel, Laurent; Brown, Eric
Tetrahedron Letters, 1993 , vol. 34, # 18 p. 2957 - 2960
反应条件
sodium hydroxide; acetic anhydride in water--are; water
参考文献
Bayer Aktiengesellschaft
Patent: US4748163 A1, 1988 ;
反应条件
tri-cyclo-hexyl-phosphine; [RhCl(η2:η2-cycloocta-1,5-diene)]2 in acetonitrile T=60°C; Racemization; 48 h;
参考文献
Shiraiwa, Tadashi; Sakata, Shinji; Natsuyama, Hisashi; Fujishima, Keiko; Miyazaki, Hideya; et al.
Bulletin of the Chemical Society of Japan, 1992 , vol. 65, # 4 p. 965 - 970
反应条件
sodium carbonate in 1,4-dioxane; water T=20°C; Inert atmosphere;
参考文献
Kim, Yongju; Kim, Jonghoon; Park, Seung Bum
Organic Letters, 2009 , vol. 11, # 1 p. 17 - 20
反应条件
lithium hydroxide hydrate in methanol T=20°C; 2 h;
参考文献
Bressi, Jerome C.; Jong, Ron de; Wu, Yiqin; Jennings, Andy J.; Brown, Jason W.; O'Connell, Shawn; Tari, Leslie W.; Skene, Robert J.; Vu, Phong; Navre, Marc; Cao, Xiaodong; Gangloff, Anthony R.
Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 10 p. 3138 - 3141
反应条件
sodium hydroxide in ethanol 0.5 h; Heating; Yield given;
参考文献
Morgan, Jacqueline; Pinhey, John T.; Sherry, Christopher J.
Journal of the Chemical Society - Perkin Transactions 1, 1997 , # 5 p. 613 - 619
反应条件
1: pyridine / CHCl3 / 1 h / 40 °C 2: aq. NaOH / ethanol / 0.5 h / Heating View Scheme
参考文献
Morgan, Jacqueline; Pinhey, John T.; Sherry, Christopher J.
Journal of the Chemical Society - Perkin Transactions 1, 1997 , # 5 p. 613 - 619
反应条件
1.1: Raney nickel / methanol / 20 °C 1.2: 50 - 64 °C 2.1: methanol / 20 °C View Scheme
参考文献
Yang, Yihua; Liu, Shouxin; Li, Junzhang; Tian, Xia; Zhen, Xiaoli; Han, Jianrong
Synthetic Communications, 2012 , vol. 42, # 17 p. 2540 - 2554
反应条件
acetic acid nachfolgend Aufbewahren mit Acetanhydrid;
参考文献
Knoop; Blanco
Hoppe-Seyler's Zeitschrift fuer Physiologische Chemie, 1925 , vol. 146, p. 269,273