1: With N,N,N',N'-tetramethylguanidine in toluene T=50°C; 1 h; Inert atmosphere; 2: With methanesulfonyl chloride in toluene T=0 - 20°C; 3 h; Inert atmosphere;

tert.-butylnitrite; 2,2,6,6-tetramethyl-1-piperidinyloxy, free radical in 1,4-dioxane T=90°C; 12 h; stereoselective reaction;

1: potassium tert-butylate / benzene / 20 °C / |Inert atmosphere; |Reflux 2: 2,2,6,6-tetramethyl-1-piperidinyloxy, free radical; tert.-butylnitrite / 1,4-dioxane / 12 h / 90 °C View Scheme

sodium acetate; acetic anhydride 24 h;