5-氯-1-苯基-1H-四唑合成路线 （共 21 条）
反应条件
N-chloro-succinimide; sodium azide; [14C]-Tetramethylammonium bromide in chloroform; water 1.) 0 deg C, 5 min, 2.) 0 deg C, 45 min;
参考文献
Collibee; Nakajima; Anselme
Journal of Organic Chemistry, 1995 , vol. 60, # 2 p. 468 - 469
反应条件
sodium azide; tetrabutylammomium bromide in water; toluene 1.5 h; Ambient temperature;
参考文献
Alves, Jose A.C.; Johnstone, Robert A.W.
Synthetic Communications, 1997 , vol. 27, # 15 p. 2645 - 2650
反应条件
1: 85 percent / gas. Cl2 / CCl4 / 0 °C 2: 100 percent / sodium azide, tetra-n-butylammonium bromide / H2O; toluene / 1.5 h / Ambient temperature View Scheme
参考文献
Synthetic Communications, , vol. 27, # 15 p. 2645 - 2650
参考文献
Journal fuer Praktische Chemie (Leipzig), , vol. <2>134, p. 282,297
反应条件
hydrogenchloride; water; copper; sodium nitrite
参考文献
Journal fuer Praktische Chemie (Leipzig), , vol. <2>134, p. 282,297
反应条件
1: 63 percent / K2CO3 / acetonitrile / 18 h / Heating 2: 14 percent / ammonium formate / Pd/C / ethanol / 0.17 h / Heating View Scheme
参考文献
Lowe, John A.; Ewing, Frank E.; Drozda, Susan E.
Synthetic Communications, 1989 , vol. 19, # 17 p. 3027 - 3036
参考文献
Bristol-Myers Squibb Company
Patent: US2007/249579 A1, 2007 ;
Location in patent: Page/Page column 18; 22 ;
反应条件
in DMF (N,N-dimethyl-formamide) T=40°C;
参考文献
ABBOTT GMBH and CO. KG
Patent: WO2004/55024 A1, 2004 ;
Location in patent: Page/Page column 25 ;
WO 2004/055024 A1
反应条件
1: 80 percent / sodium hydride / various solvent(s); tetrahydrofuran / 20 °C 2: 100 percent / 3 h / 150 °C 3: 92 percent / methanol / 3 h / Photolysis 4: acetonitrile / UV-irradiation View Scheme
参考文献
Frija, Luis M. T.; Khmelinskii, Igor V.; Cristiano, M. Lurdes S.
Journal of Organic Chemistry, 2006 , vol. 71, # 9 p. 3583 - 3591
反应条件
in tetrahydrofuran T=20°C; 4 h;
参考文献
Brigas, Amadeu F.; Clegg, William; Dillon, Christopher J.; Fonseca, Custodia F.C.; Johnstone, Robert A.W.
Journal of the Chemical Society. Perkin Transactions 2, 2001 , # 8 p. 1315 - 1324
