3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-十七氟癸基异氰酸酯合成路线 （共 5 条）
→
142010-50-23,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-十七氟癸基异氰酸酯
反应条件
T=70 - 80°C; 1 h; Yield given;
参考文献
Journal of Fluorine Chemistry, , vol. 56, # 1 p. 85 - 92
89373-67-14,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,11-十七氟十一酰氯
→
142010-50-23,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-十七氟癸基异氰酸酯
反应条件
1: With sodium azide in water; acetone T=10 - 15°C; 2: in cyclohexane Curtius Rearrangement; Further stages.;
参考文献
Wathier; Polidori; Ruiz; Fabiano; Pucci
New Journal of Chemistry, 2001 , vol. 25, # 12 p. 1588 - 1599
2043-53-01,1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8-十七氟-10-碘庚烷
→
142010-50-23,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-十七氟癸基异氰酸酯
反应条件
1: 1.) Mg / 1.) Et2O, 35 deg C, 2 h, 2.) Et2O, 5-10 deg C, 15 min 2: 92 percent / PCl5 / 1.) RT, 0.5 h, 2.) 110 deg C, 3 h 3: Me3SiN3 / 0.5 h / 15 - 20 °C 4: 1 h / 70 - 80 °C View Scheme
参考文献
Journal of Fluorine Chemistry, , vol. 56, # 1 p. 85 - 92
→
142010-50-23,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-十七氟癸基异氰酸酯
反应条件
1: 92 percent / PCl5 / 1.) RT, 0.5 h, 2.) 110 deg C, 3 h 2: Me3SiN3 / 0.5 h / 15 - 20 °C 3: 1 h / 70 - 80 °C View Scheme
参考文献
Journal of Fluorine Chemistry, , vol. 56, # 1 p. 85 - 92
142010-50-23,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-十七氟癸基异氰酸酯+
→
反应条件
1: phenyl isothiocyanate; 4-methyl benzyl amine in dichloromethane T=55 - 60°C; 8 - 12 h; 2: 3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodecylisocyanate in dichloromethane T=60°C; 2.5 h;
参考文献
FLUOROUS TECHNOLOGIES INCORPORATED
Patent: WO2004/7407 A2, 2004 ;
Location in patent: Page 58, 59, 61 ;
