哌嗪(六水)合成路线

ZHEJIANG JIANFENG HAIZHOU PHARMACEUTICAL CO., LTD.; SHANGHAI KUOIKEE LABORATORIES CO., LTD.; Shi, Mingfeng; Li, Dan; Xu, Ling
Patent: US2013/90475 A1, 2013 ;
Location in patent: Paragraph 0029; 0030 ;

142-63-2哌嗪(六水)+

19572-11-3

51940-44-4吡哌酸

参考文献

Dainippon Pharmaceutical Co., Ltd.
Patent: US3962443 A1, 1976 ;

68077-26-97-氯-1-乙基-6-氟-1,4-二氢-4-羰基喹啉-3-羧酸+

142-63-2哌嗪(六水)

70458-96-7诺氟沙星

参考文献

Kyorin Seiyaku Kabushiki Kaisha
Patent: US4448962 A1, 1984 ;

55436-41-41,4-二(苯并[1,3]二氧杂环戊烯-5-基甲基)哌嗪

参考文献

Farmaceutici Geymonat Sud S.p.A.
Patent: US4225714 A1, 1980 ;

590-92-13-溴丙酸+

142-63-2哌嗪(六水)

5649-49-01,4-双(2-羧乙基)哌嗪

参考文献

Saupe, Sebastian M.; Leubner, Stephanie; Betz, Michael; Klebe, Gerhard; Steinmetzer, Torsten
Journal of Medicinal Chemistry, 2013 , vol. 56, # 3 p. 820 - 831

32669-06-0双苯甲醇-β-氯乙基醚+

142-63-2哌嗪(六水)

60703-69-71-(2-二苯甲基氧基-乙基)-哌嗪

参考文献

Rosenthal, Sandra J.; Tomlinson, Ian D.; Kippeny, Tadd
Patent: US2005/192430 A1, 2005 ;