3-甲基-2-丁烯基硼酸频那醇酯合成路线 （共 23 条）
反应条件
1: 4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl-4',4',5',5'-tetramethyl-1,3,2-dioxaborolane With bis(dibenzylideneacetone)-palladium(0) 0.0833333 h; Inert atmosphereSealed tube; 2: 2-methyl-3-buten-2-yl acetate in dimethyl sulfoxide T=50°C; 24 h; Inert atmosphereSealed tube;
参考文献
Beveridge, Ramsay E.; Batey, Robert A.
Organic Letters, 2014 , vol. 16, # 9 p. 2322 - 2325
反应条件
1: prenyl bromide With iodine; magnesium in diethyl ether T=-20°C; Inert atmosphere; 2: With boric acid trimethyl ester in tetrahydrofuran T=-78 - 20°C; 3: 2,3-dimethylbutane-2,3-diol With acetic acid in tetrahydrofuran T=20°C;
参考文献
Gerbino, Dario C.; Mandolesi, Sandra D.; Schmalz, Hans-Guenther; Podesta, Julio C.
European Journal of Organic Chemistry, 2009 , # 23 p. 3964 - 3972
反应条件
potassium acetate; palladium dichloride in tetrahydrofuran T=60°C; 12 h; Inert atmosphere;
参考文献
Yang, Yang; Buchwald, Stephen L.
Journal of the American Chemical Society, 2013 , vol. 135, # 29 p. 10642 - 10645
反应条件
[Pd(C,N-C6H4CH2NMe2)Cl]2; toluene-4-sulfonic acid in methanol; dimethyl sulfoxide T=50°C;
参考文献
Dutheuil, Guillaume; Selander, Nicklas; Szabo, Kalman J.; Aggarwal, Varinder K.
Synthesis, 2008 , # 14 SPEC. ISS. art. no. C02308SS, p. 2293 - 2297
反应条件
magnesium; (E)-2,6-diisopropyl-N-(pyridin-2-ylmethylene)aniline iron(II) chloride in diethyl ether react. diene with 1.5 equivs. of boron compd. in Et2O in the presence ofiron complex and Mg at 23°C for 4 min-4 h;
参考文献
Journal of the American Chemical Society, , vol. 131, # 36 p. 12915 - 12917
反应条件
(E)-1,1-bis(3,5-dimethylphenyl)-N-(pyridin-2-ylmethylene)methanamine iron(II) chloride dichloromethane solvate; magnesium in diethyl ether T=23°C; 3 h; Inert atmosphere; regioselective reaction;
参考文献
Journal of the American Chemical Society, , vol. 131, # 36 p. 12915 - 12917
反应条件
[Pt(dba)2]; triphenyl-arsane; triethylamine in toluene T=50°C; borylation; 16 h;
参考文献
Murata, Miki; Watanabe, Shinji; Masuda, Yuzuru
Tetrahedron Letters, 2000 , vol. 41, # 31 p. 5877 - 5880
反应条件
[Ni0(1,5-cyclooctadiene)2]; triphenylphosphine in ethyl acetate T=60°C; 12 h; Inert atmosphere;
参考文献
Organic Letters, , vol. 14, # 6 p. 1416 - 1419
反应条件
1: 4-(N,N-dimethlyamino)pyridine / dichloromethane / Inert atmosphere 2: [Ni0(1,5-cyclooctadiene)2]; triphenylphosphine / ethyl acetate / 12 h / 60 °C / Inert atmosphere View Scheme
参考文献
Organic Letters, , vol. 14, # 6 p. 1416 - 1419
反应条件
1.1: 4-(N,N-dimethlyamino)pyridine; triethylamine / dichloromethane / 36 h / 20 °C / |Inert atmosphere 2.1: bis(dibenzylideneacetone)-palladium(0) / 0.08 h / |Inert atmosphere; |Sealed tube 2.2: 24 h / 50 °C / |Inert atmosphere; |Sealed tube View Scheme
参考文献
Organic Letters, , vol. 16, # 9 p. 2322 - 2325
