顺-3,7-二甲基-2,6-辛二烯-1-醇乙酸酯合成路线 （共 54 条）
反应条件
1: 11 g / 2N KOH / methanol 2: 73 percent / NaI , anhydrous NaOAc, zinc powder / acetic acid / 1.5 h 3: 1.) Li / 2.) ether / pet. ether , 10 min , -20 deg C 4: 96 percent / KOH / methanol 5: 50 percent / ethanol / 4 h / Heating 6: 1.) NaI , NaOAc , 2.) SnCl2 , POCl3 / 1.) Propionic acid , AcOH , 30 min , 2.) pyridine , 10 + 60 min , RT View Scheme
参考文献
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. <B> 20, # 4 p. 340 - 342
反应条件
1: 1.) Li / 2.) ether / pet. ether , 10 min , -20 deg C 2: 96 percent / KOH / methanol 3: 50 percent / ethanol / 4 h / Heating 4: 1.) NaI , NaOAc , 2.) SnCl2 , POCl3 / 1.) Propionic acid , AcOH , 30 min , 2.) pyridine , 10 + 60 min , RT View Scheme
参考文献
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. <B> 20, # 4 p. 340 - 342
反应条件
1: 96 percent / KOH / methanol 2: 50 percent / ethanol / 4 h / Heating 3: 1.) NaI , NaOAc , 2.) SnCl2 , POCl3 / 1.) Propionic acid , AcOH , 30 min , 2.) pyridine , 10 + 60 min , RT View Scheme
参考文献
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. <B> 20, # 4 p. 340 - 342
反应条件
1: 50 percent / ethanol / 4 h / Heating 2: 1.) NaI , NaOAc , 2.) SnCl2 , POCl3 / 1.) Propionic acid , AcOH , 30 min , 2.) pyridine , 10 + 60 min , RT View Scheme
参考文献
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. <B> 20, # 4 p. 340 - 342
反应条件
1,3,2-benzodithiazole 1,1,3,3-tetraoxide T=20°C;
参考文献
Synthesis, , # 22 p. 3625 - 3632
参考文献
Journal of Organic Chemistry, , vol. 46, p. 765 - 770
反应条件
sodium acetate; sodium iodide; tin(ll) chloride; trichlorophosphate 1.) Propionic acid , AcOH , 30 min , 2.) pyridine , 10 + 60 min , RT; Yield given. Multistep reaction;
参考文献
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. <B> 20, # 4 p. 340 - 342
反应条件
hydrogenchloride; citrate buffer in water T=25°C; 25 h; var. pH and reagents; Rate constantProduct distribution;
参考文献
Journal of Organic Chemistry, , vol. 54, # 5 p. 1032 - 1036
反应条件
1: SeO2 / ethanol; pyridine / 1 h / Heating 2: NaBH4 / diethyl ether; methanol / 1 h 3: 19 percent Chromat. / BF3-etherate / CH2Cl2 / 0.5 h 4: 79 percent / H2 / PtO2 / ethanol / 10 h / 760 Torr / Ambient temperature 5: 48 percent / RuO2*xH2O/NaIO4 / CCl4 / 2.5 h / 20 °C 6: 5 mg / K2CO3 / m-xylene / 5 h / Heating 7: diisopropylamine/n-BuLi / hexane; tetrahydrofuran / 1.5 h 8: NaIO4 / CH2Cl2; H2O / 0.58 h / Ambient temperature 9: toluene / 5 h / Heating 10: 77 percent / DIBAL / tetrahydrofuran / 20 h View Scheme
参考文献
Kitagawa, Isao; Tsujii, Shinji; Nishikawa, Fumiko; Shibuya, Hirotaka
Chemical & Pharmaceutical Bulletin, 1983 , vol. 31, # 8 p. 2639 - 2651
反应条件
1: SeO2, salicylic acid, tert-butyl hydroperoxide / CH2Cl2 / 27 h / Ambient temperature 2: PDC / CH2Cl2 / 10 h / Ambient temperature 3: 1.) n-BuLi / 1.) THF, -78 deg C, 2 h, 2.) THF, -78 deg C, 3 h 4: p-toluenesulfonic acid / CH2Cl2 / 3 h / Ambient temperature 5: MeOK / cyclohexane / 2 h / 38 °C View Scheme
参考文献
Otera; Misawa; Onishi; et al.
Journal of Organic Chemistry, 1986 , vol. 51, # 20 p. 3834 - 3838
