2-乙酰氨基-3-(3,4-二氯苯基)丙烯酸合成路线 （共 15 条）
反应条件
hydrogen; lt;Rh(1(S),5(S),6(S)-1,6-bis(diphenylphosphinoxy)spirolt;4.4gt;nonanegt;+ in methanol T=25°C; P=760 Torr; 0.166667 h;
参考文献
Journal of the American Chemical Society, , vol. 119, # 40 p. 9570 - 9571
反应条件
triethylamine in dichloromethane T=20°C;
参考文献
US2006/128613 A1, ;
Page/Page column 56 ;
US 20060128613 A1
反应条件
sulfuric acid; lithium bromide; [PdBr2(PPh3)2] in various solvent(s) T=120°C; P=45003.6 Torr; 12 h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Chemistry - A European Journal, , vol. 4, # 5 p. 935 - 941
反应条件
hydrogen; Rh[(R)-H8-BDPAB(COD)]BF4 in ethanol T=20°C; P=1551.44 Torr; 0.166667 h; Product distribution; Further Variations:Catalysts;
参考文献
Tetrahedron Asymmetry, , vol. 12, # 16 p. 2337 - 2342
反应条件
water in ethanol T=25°C; 4 h; Microbiological reaction; optical yield given as percent eeenantioselective reaction;
参考文献
Tetrahedron Asymmetry, , vol. 21, # 4 p. 457 - 460
反应条件
1: acylase I from porcine kidney, phosphate buffer / 2 h / 24.9 °C 2: H2O View Scheme
参考文献
Tetrahedron Letters, , vol. 39, # 29 p. 5269 - 5272
反应条件
1: water; acetone / 6 h / |Reflux 2: [(S)-BINAPRuCl(benzene)]Cl; hydrogen / methanol / 12 h / 20 - 50 °C / 3750.38 Torr / |Autoclave; |Inert atmosphere View Scheme
参考文献
Synthetic Communications, , vol. 43, # 21 p. 2892 - 2897
反应条件
1: sodium acetate; acetic anhydride / 3.75 h / 40 - 135 °C 2: water; acetone / 6 h / |Reflux 3: [(S)-BINAPRuCl(benzene)]Cl; hydrogen / methanol / 12 h / 20 - 50 °C / 3750.38 Torr / |Autoclave; |Inert atmosphere View Scheme
参考文献
Synthetic Communications, , vol. 43, # 21 p. 2892 - 2897
参考文献
Tetrahedron Letters, , vol. 39, # 29 p. 5269 - 5272
反应条件
1: acylase I from porcine kidney, phosphate buffer / 2 h / 24.9 °C 2: H2O View Scheme
参考文献
Tetrahedron Letters, , vol. 39, # 29 p. 5269 - 5272
