2-乙基-1,3,5-三硝基苯合成路线 （共 8 条）
反应条件
1: ammonium sulfide 3: fuming hydrochloric acid View Scheme
参考文献
Brady; Day; Allam
Journal of the Chemical Society, 1928 , p. 981
反应条件
1.1: 48 percent / ammonia; H2S / dioxane / 35 - 40 °C 2.1: NaNO2; AcOH; H2SO4 / H2O / 1 h / 20 - 25 °C 2.2: 76 percent / Cu2O / ethanol; H2O / 1.5 h / 20 °C View Scheme
参考文献
Brady; Day; Allam
Journal of the Chemical Society, 1928 , p. 981
反应条件
sulfuric acid; nitric acid
Erwaermen auf 100grad;
参考文献
Weisweiller
Monatshefte fuer Chemie, 1900 , vol. 21, p. 39
Full Text View citing articles Show Details
Schultz
Chemische Berichte, 1909 , vol. 42, p. 2634
参考文献
Weisweiller
Monatshefte fuer Chemie, 1900 , vol. 21, p. 39
参考文献
Schultz,G.; Flachslaender
Journal fuer Praktische Chemie (Leipzig), 1902 , vol. <2> 66, p. 155
Full Text Show Details
Weisweiller
Monatshefte fuer Chemie, 1900 , vol. 21, p. 39
反应条件
1.1: 48 percent / ammonia; H2S / dioxane / 35 - 40 °C
2.1: NaNO2; AcOH; H2SO4 / H2O / 1 h / 20 - 25 °C
2.2: 76 percent / Cu2O / ethanol; H2O / 1.5 h / 20 °C
3.1: 81 percent / formic acid; Et3N / Pd/C / acetonitrile / 0.42 h / Heating
4.1: aq. HBr; NaNO2 / H2O / 0.17 h / 0 °C
4.2: urea / H2O / 0.08 h
4.3: 87 percent / CuSO4*5H2O; Cu; aq. HBr / H2O / 1 h / 80 °C
5.1: 2 percent / NaCN / dimethylsulfoxide / 2 h / 20 °C
View Scheme
参考文献
Buehler, Sigrid; Lagoja, Irene; Giegrich, Heiner; Stengele, Klaus-Peter; Pfleiderer, Wolfgang
Helvetica Chimica Acta, 2004 , vol. 87, # 3 p. 620 - 659
反应条件
1.1: 48 percent / ammonia; H2S / dioxane / 35 - 40 °C
2.1: NaNO2; AcOH; H2SO4 / H2O / 1 h / 20 - 25 °C
2.2: 76 percent / Cu2O / ethanol; H2O / 1.5 h / 20 °C
3.1: 81 percent / formic acid; Et3N / Pd/C / acetonitrile / 0.42 h / Heating
4.1: aq. HBr; NaNO2 / H2O / 0.17 h / 0 °C
4.2: urea / H2O / 0.08 h
4.3: 87 percent / CuSO4*5H2O; Cu; aq. HBr / H2O / 1 h / 80 °C
View Scheme
参考文献
Buehler, Sigrid; Lagoja, Irene; Giegrich, Heiner; Stengele, Klaus-Peter; Pfleiderer, Wolfgang
Helvetica Chimica Acta, 2004 , vol. 87, # 3 p. 620 - 659
反应条件
hydrogen sulfide; ammonia in 1,4-dioxane
T=35 - 40°C;
参考文献
Buehler, Sigrid; Lagoja, Irene; Giegrich, Heiner; Stengele, Klaus-Peter; Pfleiderer, Wolfgang
Helvetica Chimica Acta, 2004 , vol. 87, # 3 p. 620 - 659
