4-甲基-5-(beta-羟乙基)噻唑合成路线 (共 90 条)
反应条件
1: aqueous phosphoric acid 2: dichloromethane / -60 °C 3: pyridine; aqueous formic acid View Scheme
参考文献
Journal of the American Chemical Society, , vol. 75, p. 4456
反应条件
pyridine; formic acid
参考文献
Journal of the American Chemical Society, , vol. 75, p. 4456
反应条件
in methanol 2.2 h; Heating;
参考文献
Zoltewicz, John A.
Synthesis, 1980 , # 3 p. 218 - 219
反应条件
in methanol 3.8 h; Heating;
参考文献
Zoltewicz, John A.
Synthesis, 1980 , # 3 p. 218 - 219
反应条件
sulphite in water T=25°C; pH 6.27 (phosphate buffer), ionic strength 1.0 M (KCl); pH and concentration dependence; Rate constant;
参考文献
Journal of the American Chemical Society, , vol. 103, # 16 p. 4900 - 4904
反应条件
thiaminase I from Bacillus thiaminolyticus in sodium hydroxide T=20°C; Decomposition; substitution; pH=9.1; 2 h; Title compound not separated from byproducts;
参考文献
Bioorganic Chemistry, , vol. 28, # 1 p. 45 - 48
反应条件
in methanol 24 h; Heating;
参考文献
Zoltewicz, John A.
Synthesis, 1980 , # 3 p. 218 - 219
反应条件
in methanol 72 h; Heating;
参考文献
Zoltewicz, John A.
Synthesis, 1980 , # 3 p. 218 - 219
反应条件
in methanol 26 h; Heating;
参考文献
Zoltewicz, John A.
Synthesis, 1980 , # 3 p. 218 - 219
反应条件
1: aq. HCl / ethanol 2: (i) aq. H2O2, (ii) Ba(NO3)2 3: aq. H2SO3, Py View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 9, p. 119 - 123