5-苯基异噁唑-3-羧酸乙酯合成路线 （共 11 条）
反应条件
sodium hydrogencarbonate in water T=20°C;
参考文献
KATHOLIEKE UNIVERSITEIT LEUVEN, K.U. LEUVEN Randamp;;D; reMYND; GRIFFIOEN, Gerard; VAN DOOREN, Tom; ROJAS DE LA PARRA, Veronica; MARCHAND, Arnaud; ALLASIA, Sara; KILONDA, Amuri; CHALTIN, Patrick
Patent: WO2010/142801 A1, 2010 ;
Location in patent: Page/Page column 162-163 ;
WO 2010/142801 A1
反应条件
palladium diacetate; potassium carbonate; 2-(dicyclohexylphosphino)-2',4',6'-tri-i-propyl-1,1’-biphenyl in acetone T=50°C; Inert atmosphereGlovebox;
参考文献
Tschaen, Brittany A.; Schmink, Jason R.; Molander, Gary A.
Organic Letters, 2013 , vol. 15, # 3 p. 500 - 503
参考文献
Bhosale, Sandeep; Kurhade, Santosh; Vyas, Samir; Palle, Venkata P.; Bhuniya, Debnath
Tetrahedron, 2010 , vol. 66, # 50 p. 9582 - 9588
参考文献
Bhosale, Sandeep; Kurhade, Santosh; Vyas, Samir; Palle, Venkata P.; Bhuniya, Debnath
Tetrahedron, 2010 , vol. 66, # 50 p. 9582 - 9588
反应条件
ammonium cerium(IV) nitrate in N,N-dimethyl-formamide T=0°C; Cycloaddition;
参考文献
Bulletin of the Chemical Society of Japan, , vol. 72, # 10 p. 2277 - 2285
反应条件
1.1: n-BuLi / tetrahydrofuran; hexane / 1 h / -78 - 20 °C 1.2: 40 percent / tetrahydrofuran; hexane / 16 h / -78 - 20 °C 2.1: 94 percent / TsOH*H2O / toluene / 6 h / Heating View Scheme
参考文献
Synthesis, , # 15 p. 2515 - 2522
反应条件
hydroxylamine hydrochloride; sodium carbonate in water
参考文献
Journal of Organic Chemistry USSR (English Translation), , vol. 2, p. 2034 - 2037
Zhurnal Organicheskoi Khimii, , vol. 2, p. 2075 - 2078
参考文献
Atti della Accademia Nazionale dei Lincei, Classe di Scienze Fisiche, Matematiche e Naturali, Rendiconti, , vol. <8> 13, p. 39,40
反应条件
n-butyllithium 1.) THF, 0 deg C, 30 min, 2.) THF, 0 deg C, 2 h; r.t., 12 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Archiv der Pharmazie, , vol. 328, # 5 p. 437 - 443
反应条件
(i) NaOMe, AcNMe2, MeOH, (ii) /BRN= 878250/, AcCl; Multistep reaction;
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 26, # 10 p. 3254 - 3256
