1: With (S)-(+)-N-acetyl phenylglycine in methanol; acetone T=-30 - 0°C; 48 h; 2: With sodium hydroxide in dichloromethane; water 0.5 h; Product distribution / selectivity;
参考文献
CHONG KUN DANG PHARMACEUTICAL CORP.
Patent: WO2007/91753 A1, 2007 ;
Location in patent: Page/Page column 14-15 ;
1: With (S)-(+)-N-acetyl phenylglycine in ethanol T=-30 - -20°C; 48 h; 2: With sodium hydroxide in dichloromethane; water 0.5 h; Product distribution / selectivity;
