3,4,5-三甲氧基苯乙腈合成路线 （共 36 条）
反应条件
sodium azide; TEA; diethylphosphinoethane; [bis(2-methoxyethyl)amino]-sulfur trifluoride in dichloromethane; dimethyl sulfoxide T=0°C; 50 h;
参考文献
Tetrahedron Letters, , vol. 49, # 5 p. 914 - 918
反应条件
oxalic acid diimidazolide in benzene 1.) r.t., 15 min, 2.) 68-70 deg C, 1 h;
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 39, # 1 p. 187 - 189
反应条件
1: SOCl2 / dioxane / 20 °C 2: acetonitrile / 20 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 11, # 16 p. 2205 - 2208
反应条件
in water; ethyl acetate; N,N-dimethyl-formamide
反应条件
diethylene glycol monoethyl ether; sodium amide in ethylene glycol dimethyl ether 1.) 45 deg C, 2 h, 2.) -10 deg C, 2 h, 3.) -30 deg C, 4.5 h;
参考文献
Synthetic Communications, , vol. 19, # 19 p. 3323 - 3330
参考文献
Journal of the American Chemical Society, , vol. 73, p. 5495
反应条件
1: 70 percent / LAH / tetrahydrofuran 2: 80 percent / PBr3, triethylamine / CCl4 / 1) 1h, 0 degC 2) 3h, roomtemp. 3: 75 percent / dimethylsulfoxide / Ambient temperature View Scheme
参考文献
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 21, # 3 p. 173 - 175
反应条件
1: NaBH4 / methanol / 20 °C 2: SOCl2 / dioxane / 20 °C 3: acetonitrile / 20 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 11, # 16 p. 2205 - 2208
反应条件
in dimethyl sulfoxide Ambient temperature;
参考文献
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 21, # 3 p. 173 - 175
反应条件
1: H2O 2: dimethylformamide 3: K2CO3 / acetone View Scheme
参考文献
Tetrahedron, , vol. 29, p. 1931 - 1939
