5-(三甲基硅烷基)-4-戊炔-1-醇合成路线 （共 21 条）
反应条件
n-butyllithium Inert atmosphere;
参考文献
Tresse, Cedric; Guissart, Celine; Schweizer, Stephane; Bouhoute, Yassine; Chany, Anne-Caroline; Goddard, Mary-Lorene; Blanchard, Nicolas; Evano, Gwilherm
Advanced Synthesis and Catalysis, 2014 , vol. 356, # 9 p. 2051 - 2060
反应条件
Rexyn-101 in diethyl ether T=20°C; 3 h;
参考文献
Bunce, Richard A.; Hertzler, Donald V.
Journal of Organic Chemistry, 1986 , vol. 51, # 18 p. 3451 - 3453
反应条件
1: 5-hydroxypentyne With n-butyllithium T=-60°C; 2: chloro-trimethyl-silane 3: With hydrogenchloride
参考文献
EP1528056 A1, ;
Page/Page column 8; 28 ;
反应条件
zinc in acetonitrile T=100°C; 12 h;
参考文献
Sugita, Hikaru; Hatanaka, Yasuo; Hiyama, Tamejiro
Chemistry Letters, 1996 , # 5 p. 379 - 380
反应条件
n-butyllithium in tetrahydrofuran; hexane 3 h; Ambient temperature;
参考文献
Plueg, Carsten; Friedrichsen, Willy; Debaerdemaeker, Tony
Advanced Synthesis and Catalysis, 1997 , vol. 339, # 3 p. 205 - 216
反应条件
1: 1) BuLi / 1) - 78 to -35 deg C, 2) -78 to 25 deg C 2: K2CO3 / methanol / 0.75 h / 0 °C View Scheme
参考文献
Tetrahedron, , vol. 41, # 17 p. 3559 - 3568
反应条件
1: trimethylsilylacetylene With n-butyllithium Metallation; 2: trimethylene oxide Alkylation;
参考文献
Journal of Organic Chemistry, , vol. 64, # 4 p. 1291 - 1301
反应条件
n-butyllithium; triisopropylsilyl chloride 1.) hexane, THF, r.t., 1 h, 2.) hexane, 0 deg C, 30 min, r.t., 17 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 1085 - 1094
反应条件
n-butyllithium; chloro-trimethyl-silane 1.) hexane, THF, r.t., 1 h, 2.) hexane, 0 deg C, 30 min, r.t., 17 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 1085 - 1094
反应条件
(i) Et2O, (ii) /BRN= 1209232/, CuCl; Multistep reaction;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 361 - 366
