1-甲基-5-巯基-1H-四氮唑合成路线 （共 24 条）
反应条件
hydrogenchloride; sodium hydroxide; magnesium sulfate; sodium nitrite; aluminium trichloride in ethanol; water; toluene
反应条件
in ice-water; ethanol; water; ethyl acetate
反应条件
aluminium trichloride in water; toluene
反应条件
hydrazine in dichloromethane 0.25 h; Ambient temperaturefurther reagents;
参考文献
Maiti, Samarendra N.; Spevak, Paul; Singh, Maya Prakash; Micetich, Ronald G.; Reddy, A. V. Narender
Synthetic Communications, 1988 , vol. 18, # 6 p. 575 - 582
反应条件
sodium azide in ethanol T=70°C; Cyclization; 3 h;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 10, # 13 p. 1421 - 1425
参考文献
Journal fuer Praktische Chemie (Leipzig), , vol. <2>124, p. 275
参考文献
Terreni, Marco; Pagani, Giuseppe; Ubiali, Daniela; Fernandez-Lafuente, Roberto; Mateo, Cesar; Guisan, Jose M.
Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 18 p. 2429 - 2432
反应条件
pyridine; hydrogenchloride; sodium hydroxide; nitrogen in methanol; dichloromethane; water
参考文献
Bristol-Myers Company
Patent: US4868294 A1, 1989 ;
反应条件
boron trifluoride in acetonitrile T=30°C; 1.5 h;
参考文献
Saikawa; Takano; Momonoi; et al.
Chemical and Pharmaceutical Bulletin, 1985 , vol. 33, # 12 p. 5534 - 5538
