吡嗪-2,5-二羧酸二甲酯合成路线 （共 10 条）
参考文献
Agyin, Joseph K.; Santhamma, Bindu; Roy, Sudipa S.
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 23 p. 6455 - 6458
反应条件
trifluoroacetic acid in dichloromethane T=20°C;
参考文献
Rodrigues, Anabela; Ferreira, Paula M.T.; Monteiro, Luis S.
Tetrahedron, 2004 , vol. 60, # 38 p. 8489 - 8496
反应条件
in methanol; chloroform
参考文献
The Ohio State University
Patent: US4871736 A1, 1989 ;
反应条件
ethanol T=125°C; anschliessend mit Methanol und konz. H2SO4;
参考文献
Ellingson; Henry
Journal of the American Chemical Society, 1949 , vol. 71, p. 2798
反应条件
1: SeO2 / pyridine; H2O / 18 h / Heating 2: 8.98 g / SOCl2 / 8 h / Heating View Scheme
参考文献
Agyin, Joseph K.; Santhamma, Bindu; Roy, Sudipa S.
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 23 p. 6455 - 6458
反应条件
1: H2O 2: HCl View Scheme
参考文献
Mager; Berends
Recueil des Travaux Chimiques des Pays-Bas, 1958 , vol. 77, p. 842,847
反应条件
sodium azide; sulfuric acid; trichloroacetic acid
参考文献
Sharefkin; Spoerri
Journal of the American Chemical Society, 1951 , vol. 73, p. 1637
参考文献
Sharefkin; Spoerri
Journal of the American Chemical Society, 1951 , vol. 73, p. 1637
反应条件
potassium hydroxide
Hydrolysis.bei anschliessender Hydrierung an Palladium/Kohle;
参考文献
Felder et al.
Helvetica Chimica Acta, 1960 , vol. 43, p. 888,892
Chimia, 1959 , vol. 13, p. 263
参考文献
Spoerri; Erickson
Journal of the American Chemical Society, 1938 , vol. 60, p. 400
