1.1: potassium hexamethylsilazane / tetrahydrofuran / 2.25 h / -78 - 20 °C / Inert atmosphere 1.2: 1 h / 0 °C / Inert atmosphere 1.3: 2 h / 0 - 20 °C / Inert atmosphere 2.1: KHF2 / methanol; water / 1 h / 0 - 20 °C View Scheme

dichloro bis(acetonitrile) palladium(II); caesium carbonate; dicyclohexyl(2',6'-diisopropoxy-[1,1'-biphenyl]-2-yl)phosphine in water; tert-butyl alcohol T=100°C; Suzuki-Miyaura cross-coupling; Inert atmosphere;