2,2-二甲基-1,3-丙二醇合成路线 （共 467 条）
反应条件
Yield given. Multistep reaction;
参考文献
Backer; Keuning
Recueil des Travaux Chimiques des Pays-Bas, 1934 , vol. 53, p. 798,805
反应条件
1: 93 percent / SOCl2 / diethyl ether / 2 h / 0 °C 2: 66 percent / dimethylsulfoxide / 5 h / 120 °C 3: pyridine / 12 h / 0 °C 4: LiBr / dimethylsulfoxide / 3 h / 120 °C View Scheme
参考文献
Tetrahedron Letters, , vol. 31, # 21 p. 2975 - 2978
反应条件
1: POCl3 / CH2Cl2 / 1 h / 50 °C 2: 86 percent / tetrahydrofuran / 1 h / 20 °C View Scheme
参考文献
Ogilvie,K.K. et al.
Journal of the American Chemical Society, 1977 , vol. 99, p. 1277 - 1278
参考文献
Edmundson,R.S.
Tetrahedron, 1964 , vol. 20, p. 2781 - 2795
反应条件
1: PCl3 / CH2Cl2 2: triethylamine / tetrahydrofuran / 1 h / Ambient temperature View Scheme
参考文献
Patois, Carl; Ricard, Louis; Savignac, Philippe
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1990 , # 6 p. 1577 - 1581
反应条件
triethylamine in dichloromethane
参考文献
Fazliev,D.F. et al.
J. Gen. Chem. USSR (Engl. Transl.), 1976 , vol. 46, p. 1832 - 1838,1776 - 1781
反应条件
bis(1-methylethyl) ester of sulfurous acid; sodium t-butanolate in tetrahydrofuran; N,N-dimethyl-formamide
参考文献
King, Steven A.; Pipik, Brenda; Conlon, David A.; Bhupathy
Synthetic Communications, 1997 , vol. 27, # 4 p. 701 - 707
反应条件
2: 170 - 180 °C View Scheme
参考文献
Bartle,K.D. et al.
Tetrahedron, 1967 , vol. 23, p. 1701 - 1711
反应条件
toluene; benzenesulfonic Acid unter Entfernen des entstehenden Wassers;
参考文献
Dangy-Caye,R. et al.
Bulletin de la Societe Chimique de France, 1971 , p. 3993 - 3997
参考文献
Bartle,K.D. et al.
Tetrahedron, 1967 , vol. 23, p. 1701 - 1711
