2,2-二甲基-1,3-丙二醇合成路线 （共 467 条）
反应条件
1: pyridine / 24 h / 10 °C 2: NaN3 / bis-(2-hydroxy-ethyl) ether / 16 h / 135 °C 3: LiAlH4 / tetrahydrofuran / 18 h / Heating View Scheme
参考文献
Fleischer,E.B. et al.
Journal of Organic Chemistry, 1971 , vol. 36, p. 3042 - 3044
反应条件
1: toluene / 20 h / Heating 2: 0.73 g / N-bromosuccinimide; AIBN / CCl4 / 16 h / Heating View Scheme
参考文献
Stones, Duane; Manku, Sukhdev; Lu, Xiaosong; Hall, Dennis G.
Chemistry - A European Journal, 2004 , vol. 10, # 1 p. 92 - 100
反应条件
sulfuric acid in water T=90°C;
参考文献
F. HOFFMANN-LA ROCHE AG
Patent: WO2007/48717 A1, 2007 ;
Location in patent: Page/Page column 23 ;
反应条件
1: 90 percent / p-toluenesulfonic acid / benzene / 4.6 h / Heating 2: 81 percent / CrO3, 3,5-dimethylpyrazole / CH2Cl2 / 0.17 h View Scheme
参考文献
Lednicer; Von Voigtlander; Emmert
Journal of Medicinal Chemistry, 1981 , vol. 24, # 3 p. 341 - 346
反应条件
sulfuric acid in water 41 h; extraction by hexane; Yield given;
参考文献
Babler, James H.; Spina, Kenneth P.
Synthetic Communications, 1984 , vol. 14, # 1 p. 39 - 44
反应条件
toluene-4-sulfonic acid in benzene 12 h; Inert atmosphereReflux;
参考文献
Banerjee, Moloy; Shukla, Ruchi; Rathore, Rajendra
Journal of the American Chemical Society, 2009 , vol. 131, p. 1780 - 1786
反应条件
ueber mehrere Stufen;
参考文献
Cowie et al.
Chemistry and Industry (London, United Kingdom), 1959 , p. 1248
Full Text Show Details
Musgrave
Chemistry and Industry (London, United Kingdom), 1957 , p. 1152
反应条件
ueber mehrere Stufen;
参考文献
Cowie et al.
Chemistry and Industry (London, United Kingdom), 1959 , p. 1248
Full Text Show Details
Musgrave
Chemistry and Industry (London, United Kingdom), 1957 , p. 1152
反应条件
(i) (irradiation), BBr3, (ii) /BRN= 605291/; Multistep reaction;
参考文献
Bowie,R.A.; Musgrave,O.C.
Journal of the Chemical Society [Section] C: Organic, 1970 , p. 485 - 488
参考文献
Coutts,I.G.C. et al.
Journal of the Chemical Society [Section] C: Organic, 1970 , p. 488 - 493
