4-氯-3-硝基三氟甲苯合成路线 （共 136 条）
反应条件
pyridine; hydrogenchloride; bromine; iron(III) chloride in N-methyl-acetamide; water
参考文献
E.I. DU PONT DE NEMOURS AND COMPANY
Patent: EP386892 A3, 1990 ;
参考文献
ICI AMERICAS INC.
Patent: EP425743 A1, 1991 ;
反应条件
potassium phosphate; tetrakis(triphenylphosphine) palladium(0); triphenylphosphine in tetrahydrofuran T=50°C; 24 h;
参考文献
Jiang, Biao; Kan, Ying; Zhang, Ao
Tetrahedron, 2001 , vol. 57, # 8 p. 1581 - 1584
反应条件
1: ammonia / ethanol / 120 °C 2: 1.) sodium nitrite / 1.) glacial acetic acid, concd. sulfuric acid, 10 to 20 deg C View Scheme
参考文献
Barlin, Gordon B.; Jiravinyu, Chuenjit
Australian Journal of Chemistry, 1990 , vol. 43, # 2 p. 311 - 319
反应条件
potassium tert-butylate in tert-butyl alcohol 3 - 6 h; Heating / reflux;
参考文献
US2006/47126 A1, ;
Page/Page column 26 ;
反应条件
triethylamine in ethanol 20 h; Heating;
参考文献
Paglietti, Giuseppe; Loriga, Mario
Journal of Chemical Research, Miniprint, 1986 , # 8 p. 2471 - 2491
反应条件
1: KOH 2: H2SO4 View Scheme
参考文献
Frazier,T.C. et al.
Journal of Organic Chemistry, 1961 , vol. 26, p. 2223 - 2225
反应条件
1: Na2S*9H2O 2: aq. NaOH View Scheme
参考文献
Hogg,D.R.; Robertson,A.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1979 , p. 1125 - 1128
反应条件
in N,N-dimethyl-formamide
参考文献
Sumitomo Pharmaceuticals Company, Limited
Patent: US5834454 A1, 1998 ;
反应条件
in ethanol 4 h; Heating;
参考文献
Bertha, Ferenc; Hornyak, Gyula; Zauer, Karoly; Feller, Antal; Lempert, Karoly; et al.
Tetrahedron, 1985 , vol. 41, # 14 p. 2855 - 2860
