三甲基硅烷基 2-(氟磺酰基)二氟乙酸酯合成路线 （共 16 条）
反应条件
chloro-trimethyl-silane T=105°C; P=4200.42 Torr; 6 h;
参考文献
US2007/270602 A1, ;
Page/Page column 4 ;
反应条件
1: T=0 - 100.6°C; P=4350.44 - 5925.59 Torr; 18 h; 2: With chloro-trimethyl-silane T=20 - 107.8°C; Heating / reflux; Product distribution / selectivity;
参考文献
US2007/270602 A1, ;
Page/Page column 3-4 ;
参考文献
Journal of Fluorine Chemistry, , vol. 119, # 1 p. 39 - 51
反应条件
24 h; -196 deg C upto room temp.;
参考文献
Journal of Fluorine Chemistry, , vol. 42, p. 187 - 200
参考文献
Journal of Fluorine Chemistry, , vol. 125, # 3 p. 459 - 469
参考文献
Journal of Fluorine Chemistry, , vol. 125, # 3 p. 459 - 469
反应条件
1: 2'-deoxy-3-N-methyl-3',5'-di-O-methyl-2'-methyleneuridine With NAF in toluene T=110°C; 0.5 h; Inert atmosphere; 2: trimethylsilyl-2,2-difluoro-2-(fluorosulfonyl) acetate in toluene RefluxInert atmosphere;
参考文献
Journal of Fluorine Chemistry, , vol. 130, # 3 p. 321 - 328
反应条件
NAF in diethylene glycol dimethyl ether 2 h; bath temperature 120 deg C;
参考文献
Xu, Wei; Chen, Qing-Yun
Journal of Organic Chemistry, 2002 , vol. 67, # 26 p. 9421 - 9427
反应条件
1: acrylic acid n-butyl ester With NAF in toluene 1 h; Heating; 2: trimethylsilyl-2,2-difluoro-2-(fluorosulfonyl) acetate in toluene 8 h; Heating;
参考文献
Dolbier Jr., William R.; Gautriaud, Emilie; Cai, Xiaohong
Journal of Fluorine Chemistry, 2005 , vol. 126, # 3 p. 339 - 343
反应条件
1: 2-hydroxy-pyridine With sodium hydride in acetonitrile; mineral oil T=20°C; 0.166667 h; Inert atmosphere; 2: trimethylsilyl-2,2-difluoro-2-(fluorosulfonyl) acetate With cesium fluoride in acetonitrile; mineral oil
参考文献
WO2012/7869 A2, ;
Page/Page column 90-91 ;
