反应条件
1: py2ald With N-chloro-succinimide in N,N-dimethyl-formamide T=0 - 60°C; 2: propargyl alcohol With triethylamine in N,N-dimethyl-formamide T=0 - 20°C; 19.5 h;
参考文献
ARRAY BIOPHARMA INC.; RODRIGUEZ, Martha, E.; MARESKA, David, A.; HANS, Jeremy, J.; HARVEY, Darren, M.; GRONEBERG, Robert, D.; O'SULLIVAN, Michael
Patent: WO2010/80864 A1, 2010 ;
Location in patent: Page/Page column 164-165 ;