5-乙基-3,4-二氢-2H-吡咯合成路线 （共 16 条）
反应条件
1: With hydrogenchloride in tetrahydrofuran; water T=100°C; 6.2 h; Heating / reflux; 2: With sodium hydroxide in water T=5 - 10°C; pH=9 - 10; Alkaline conditions;
参考文献
MERCKLE GMBH
Patent: EP1246825 B1, 2003 ;
Location in patent: Page 30 ;
反应条件
(η5-Me5C5)2SmCH(Me3Si)2 in benzene 96 h; Ambient temperature;
参考文献
Li; Marks
Journal of the American Chemical Society, 1996 , vol. 118, # 39 p. 9295 - 9306
反应条件
hydrogenchloride; oxygen; sodium chloride; copper dichloride; palladium dichloride in water T=60°C; 6.5 h; Yield given. Yields of byproduct given;
参考文献
Pugin, B.; Venanzi, L. M.
Journal of the American Chemical Society, 1983 , vol. 105, # 23 p. 6877 - 6881
反应条件
hydrogenchloride; oxygen; sodium chloride; copper dichloride; palladium dichloride in water T=60°C; 6 h; Yield given. Yields of byproduct given;
参考文献
Pugin, B.; Venanzi, L. M.
Journal of the American Chemical Society, 1983 , vol. 105, # 23 p. 6877 - 6881
反应条件
boric acid T=180°C; 0.75 h;
参考文献
Bacos, Daniel; Celerier, Jean-Pierre; Lhommet, Gerard
Tetrahedron Letters, 1987 , vol. 28, # 21 p. 2353 - 2354
反应条件
1: 1.) n-BuLi / 1.) THF, -78 deg C, 1 h, 2.) THF, reflux, 1 h 2: dimethylformamide / 60 °C 3: N2H4*H2O / ethanol / 60 °C 4: 95 percent Spectr. / Cp'2SmCH(SiMe3)2 / benzene-d6 / 21 °C View Scheme
参考文献
Li; Marks
Journal of the American Chemical Society, 1996 , vol. 118, # 39 p. 9295 - 9306
反应条件
1: N2H4*H2O / ethanol / 60 °C 2: 95 percent Spectr. / Cp'2SmCH(SiMe3)2 / benzene-d6 / 21 °C View Scheme
参考文献
Li; Marks
Journal of the American Chemical Society, 1996 , vol. 118, # 39 p. 9295 - 9306
反应条件
1: PdCl2, CuCl2, NaCl, 0.2 M HCl, O2 / D2O / 0.17 h / 60 °C 2: PdCl2, CuCl2, NaCl, 0.2 M HCl, O2 / H2O / 6.5 h / 60 °C View Scheme
参考文献
Pugin, B.; Venanzi, L. M.
Journal of the American Chemical Society, 1983 , vol. 105, # 23 p. 6877 - 6881
反应条件
in tetrahydrofuran; paraffin
参考文献
Striegel, Hans-Guenter; Laufer, Stefan; Tollmann, Karola; Tries, Susanne
Patent: US2003/153558 A1, 2003 ;
反应条件
diisopentyl ether Behandeln des Reaktionsgemisches mit fluessigem Ammoniak;
参考文献
Cloke
Journal of the American Chemical Society, 1929 , vol. 51, p. 1186
Full Text Show Details
de Boosere
Bulletin des Societes Chimiques Belges, 1923 , vol. 32, p. 32
Chem. Zentralbl., 1923 , vol. 94, # III p. 1162
