3-环丙基-3-氧代丙腈合成路线 (共 14 条)
反应条件
1: With hydroxylammonium sulphate; sodium hydroxide in water T=20 - 100°C; pH=8 - 11; 1.5 h; Inert atmosphere; 2: With hydrogenchloride in water T=100°C; 0.25 h; Inert atmosphere;
参考文献
Johnson, Leland; Powers, James; Ma, Fupeng; Jendza, Keith; Wang, Bing; Meredith, Erik; Mainolfi, Nello
Synthesis (Germany), 2013 , vol. 45, # 2 p. 171 - 173
反应条件
in ethanol 5 h; Heating;
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 35, # 8 p. 3235 - 3252
反应条件
hydrazine hydrate in ethanol
参考文献
Pharmacia and Upjohn S.p.A; Pharmacia and Upjohn Co.
Patent: US6218418 B1, 2001 ;
反应条件
in ethanol
6 h; Reflux;
参考文献
SCHERING CORPORATION; SHIPPS, JR., Gerald, W.; CHENG, Cliff, C.; HUANG, Xiaohua; ACHAB, Abdelghani, Abe; ORTH, Peter; VOIGT, Johannes, H.; SOUCY, Kyle, Ann
Patent: WO2010/56631 A1, 2010 ;
Location in patent: Page/Page column 159 ;
WO 2010/056631 A1