2-氨基-4-氟苯甲酸甲酯合成路线

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Portola Pharmaceuticals, Inc.
Patent: US6906063 B2, 2005 ;

参考文献

Pandey, Anjali; Volkots, Deborah L.; Seroogy, Joseph M.; Rose, Jack W.; Yu, Jin-Chen; Lambing, Joseph L.; Hutchaleelaha, Athiwat; Hollenbach, Stanley J.; Abe, Keith; Giese, Neill A.; Scarborough, Robert M.
Journal of Medicinal Chemistry, 2002 , vol. 45, # 17 p. 3772 - 3793

394-27-44-乙酰胺基-4-氟苯甲酸

117323-99-62-氨基-4-溴苯甲酸乙酯+

117324-05-72-氨基-4-氟苯甲酸甲酯

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Pfizer Inc.
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117324-05-72-氨基-4-氟苯甲酸甲酯

7471-58-13-(氯甲基)-6-(三氟甲基)吡啶

参考文献

Pandey, Anjali; Scarborough, Robert M.; Matsuno, Kenji; Ichimura, Michio; Nomoto, Yuji; Ide, Shinichi; Tsukuda, Eiji; Sasaki, Junko; Oda, Shoji
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117324-05-72-氨基-4-氟苯甲酸甲酯

16499-57-37-氟-4-喹唑啉酮

参考文献

Portola Pharmaceuticals, Inc.
Patent: US6906063 B2, 2005 ;

77287-34-4甲亚胺酸+

117324-05-72-氨基-4-氟苯甲酸甲酯

16499-57-37-氟-4-喹唑啉酮

参考文献

Pandey, Anjali; Volkots, Deborah L.; Seroogy, Joseph M.; Rose, Jack W.; Yu, Jin-Chen; Lambing, Joseph L.; Hutchaleelaha, Athiwat; Hollenbach, Stanley J.; Abe, Keith; Giese, Neill A.; Scarborough, Robert M.
Journal of Medicinal Chemistry, 2002 , vol. 45, # 17 p. 3772 - 3793