N-苄氧羰基-L-苯丙氨酸合成路线 （共 122 条）
反应条件
(i) diphenylketene, Et3N, THF, (ii) /BRN= 635782/; Multistep reaction;
参考文献
Losse,G.; Demuth,E.
Chemische Berichte, 1961 , vol. 94, p. 1762 - 1766
反应条件
N,N'-Bis(2-oxo-3-oxazolidinyl)phosphorodiamidic azide; triethylamine in dichloromethane
参考文献
Katti, S. B.; Misra, P. K.; Haq, W.; Mathur, K. B.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1988 , vol. 27, # 1-12 p. 3 - 4
反应条件
4-(N,N-dimethlyamino)pyridine; triethylamine in acetonitrile
T=4°C; 0.833333 h;
参考文献
Pardin, Christophe; Gillet, Steve M.F.G.; Keillor, Jeffrey W.
Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 24 p. 8379 - 8385
反应条件
in ethanol; ethyl acetate
参考文献
Ajinomoto Co., Inc.
Patent: US3933783 A1, 1976 ;
参考文献
Fujisawa Pharmaceutical Co., Ltd.
Patent: US3976635 A1, 1976 ;
参考文献
Goodman; Stueben
Journal of the American Chemical Society, 1959 , vol. 81, p. 3980,3982
参考文献
Bodanszky; du Vigneaud
Journal of the American Chemical Society, 1959 , vol. 81, p. 6072,6074
反应条件
pyridine in ethyl acetate
参考文献
Wieland,T. et al.
Justus Liebigs Annalen der Chemie, 1962 , vol. 655, p. 189 - 194
参考文献
Sakakibara,S.; Inukai,N.
Bulletin of the Chemical Society of Japan, 1964 , vol. 37, p. 1231 - 1232
反应条件
1: NMM / tetrahydrofuran
2: 2.) HCl / 1.) Et2O
View Scheme
参考文献
Garrouste, Patrick; Pawlowski, Macek; Tonnaire, Thierry; Sicsic, Sames; Dumy, Pascal; De Rosny, Eve; Reboud-Ravaux, Michele; Fulcrand, Pierre; Martinez, Jean
European Journal of Medicinal Chemistry, 1998 , vol. 33, # 6 p. 423 - 436
