5-甲基-3-苯基异恶唑-4-羧酸乙酯合成路线 （共 14 条）
反应条件
1: in dichloromethane T=40°C; 2 h; 2: With triethylamine in dichloromethane T=40°C; 24 h;
参考文献
Kurkowska, Joanna; Zadrozna, Irmina
Journal of Chemical Research, Miniprint, 2003 , # 5 p. 541 - 554
反应条件
sulfuric acid 28 h; Reflux;
参考文献
Takikawa, Hiroshi; Takada, Akiomi; Hikita, Katsuyoshi; Suzuki, Keisuke
Angewandte Chemie - International Edition, 2008 , vol. 47, # 39 p. 7446 - 7449
反应条件
chloroformic acid ethyl ester; triethylamine in tetrahydrofuran; dimethyl sulfoxide Inert atmosphere;
参考文献
US2010/48910 A1, ;
Page/Page column 2 ;
参考文献
Benfatti, Fides; Cardillo, Giuliana; Contaldi, Simone; Gentilucci, Luca; Mosconi, Elisa; Tolomelli, Alessandra; Juaristi, Eusebio; Reyes-Rangel, Gloria
Tetrahedron, 2009 , vol. 65, # 12 p. 2478 - 2483
反应条件
triethylamine in tetrahydrofuran T=70°C; 1 h; Microwave irradiation;
参考文献
Kalin, Jay H.; Zhang, Hankun; Gaudrel-Grosay, Sophie; Vistoli, Giulio; Kozikowski, Alan P.
ChemMedChem, 2012 , vol. 7, # 3 p. 425 - 439
反应条件
1: Benzaldoxime With pyridine; N-chloro-succinimide in chloroform Heating; 2: ethyl 3-(pyrrolidin-1-yl)but-2-enoate With triethylamine in chloroform
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 20, # 2 p. 726 - 729
反应条件
1: N-chloro-succinimide; aluminum oxide / 40 °C / Microwave irradiation 2: triethylamine / tetrahydrofuran / 1 h / 70 °C / Microwave irradiation View Scheme
参考文献
ChemMedChem, , vol. 7, # 3 p. 425 - 439
反应条件
1: water / Eintragen von wss. Natronlauge unter starker Kuehlung View Scheme
参考文献
Gazzetta Chimica Italiana, , vol. 76, p. 148,163
参考文献
Gazzetta Chimica Italiana, , vol. 76, p. 148,163
反应条件
1: water; sodium hydroxide / methanol / 4 h / 60 °C 2: borane-THF / tetrahydrofuran / 0 - 20 °C 3: manganese(IV) oxide / dichloromethane / 20 °C / Inert atmosphere View Scheme
参考文献
Kalin, Jay H.; Zhang, Hankun; Gaudrel-Grosay, Sophie; Vistoli, Giulio; Kozikowski, Alan P.
ChemMedChem, 2012 , vol. 7, # 3 p. 425 - 439
